Inverse ratio ventilation combined with PEEP in infants undergoing thoracoscopic surgery with one lung ventilation for lung cystadenomas: a randomized control trial of 63 cases

Inverse ratio ventilation combined with PEEP in infants undergoing thoracoscopic surgery with one lung ventilation for lung cystadenomas: a randomized control trial of 63 cases

OBJECTIVETo investigate the effect of inverse ratio ventilation (IRV) combined with positive end-expiratory pressure (PEEP) in infants undergoing thoracoscopic surgery with single lung ventilation (OLV) for lung cystadenomas. METHODSA total of 66 infants undergoing thoracoscopic surgery with OLV for...

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Veröffentlicht in:Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2020-07, Vol.40 (7), p.1008-1012
Hauptverfasser: Wang, Yun, Huang, Weijian, He, Mudan, Peng, Lingli, Cai, Mingyang, Yuan, Chao, Hu, Zurong, Li, Kunwei
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container_end_page 1012
container_issue 7
container_start_page 1008
container_title Nan fang yi ke da xue xue bao = Journal of Southern Medical University
container_volume 40
creator Wang, Yun
Huang, Weijian
He, Mudan
Peng, Lingli
Cai, Mingyang
Yuan, Chao
Hu, Zurong
Li, Kunwei
description OBJECTIVETo investigate the effect of inverse ratio ventilation (IRV) combined with positive end-expiratory pressure (PEEP) in infants undergoing thoracoscopic surgery with single lung ventilation (OLV) for lung cystadenomas. METHODSA total of 66 infants undergoing thoracoscopic surgery with OLV for lung cystadenomas in our hospital from February, 2018 to February, 2019 were randomized into conventional ventilation groups (group N, n=33) and inverse ventilation group (group R, n=33). Hemodynamics and respiratory parameters of the infants were recorded and arterial blood gas analysis was performed at 15 min after two lung ventilation (TLV) (T1), OLV30 min (T2), OLV60 min (T3), and 15 min after recovery of TLV (T4). Bronchoalveolar lavage fluid was collected before and after surgery to detect the expression level of advanced glycation end product receptor (RAGE). RESULTSSixty-three infants were finally included in this study. At T2 and T3, Cdyn, PaO2 and OI in group R were significantly higher (P < 0.05) and Pp
doi_str_mv 10.12122/j.issn.1673-4254.2020.07.14
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METHODSA total of 66 infants undergoing thoracoscopic surgery with OLV for lung cystadenomas in our hospital from February, 2018 to February, 2019 were randomized into conventional ventilation groups (group N, n=33) and inverse ventilation group (group R, n=33). Hemodynamics and respiratory parameters of the infants were recorded and arterial blood gas analysis was performed at 15 min after two lung ventilation (TLV) (T1), OLV30 min (T2), OLV60 min (T3), and 15 min after recovery of TLV (T4). Bronchoalveolar lavage fluid was collected before and after surgery to detect the expression level of advanced glycation end product receptor (RAGE). RESULTSSixty-three infants were finally included in this study. At T2 and T3, Cdyn, PaO2 and OI in group R were significantly higher (P &lt; 0.05) and Pp</description><identifier>ISSN: 1673-4254</identifier><identifier>DOI: 10.12122/j.issn.1673-4254.2020.07.14</identifier><language>chi</language><ispartof>Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2020-07, Vol.40 (7), p.1008-1012</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids></links><search><creatorcontrib>Wang, Yun</creatorcontrib><creatorcontrib>Huang, Weijian</creatorcontrib><creatorcontrib>He, Mudan</creatorcontrib><creatorcontrib>Peng, Lingli</creatorcontrib><creatorcontrib>Cai, Mingyang</creatorcontrib><creatorcontrib>Yuan, Chao</creatorcontrib><creatorcontrib>Hu, Zurong</creatorcontrib><creatorcontrib>Li, Kunwei</creatorcontrib><title>Inverse ratio ventilation combined with PEEP in infants undergoing thoracoscopic surgery with one lung ventilation for lung cystadenomas: a randomized control trial of 63 cases</title><title>Nan fang yi ke da xue xue bao = Journal of Southern Medical University</title><description>OBJECTIVETo investigate the effect of inverse ratio ventilation (IRV) combined with positive end-expiratory pressure (PEEP) in infants undergoing thoracoscopic surgery with single lung ventilation (OLV) for lung cystadenomas. METHODSA total of 66 infants undergoing thoracoscopic surgery with OLV for lung cystadenomas in our hospital from February, 2018 to February, 2019 were randomized into conventional ventilation groups (group N, n=33) and inverse ventilation group (group R, n=33). Hemodynamics and respiratory parameters of the infants were recorded and arterial blood gas analysis was performed at 15 min after two lung ventilation (TLV) (T1), OLV30 min (T2), OLV60 min (T3), and 15 min after recovery of TLV (T4). Bronchoalveolar lavage fluid was collected before and after surgery to detect the expression level of advanced glycation end product receptor (RAGE). RESULTSSixty-three infants were finally included in this study. 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title Inverse ratio ventilation combined with PEEP in infants undergoing thoracoscopic surgery with one lung ventilation for lung cystadenomas: a randomized control trial of 63 cases
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