Dextroplantation of Left Liver Graft in Infants

The position of the left side liver graft is important, and it could lead to complications of the hepatic vein (HV) and portal vein (PV), especially in a small child using a variant left lateral section (vLLS) graft. The purpose of this study was to evaluate the outcome of a novel technique for the...

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Veröffentlicht in:Liver transplantation 2021-02, Vol.27 (2), p.222-230
Hauptverfasser: Ahn, Sung Woo, Yi, Nam‐Joon, Kim, Hyo‐Cheol, Ahn, Hye Young, Hong, Suk Kyun, Lee, Jeong‐Moo, Cho, Jae‐Hyung, Jin, Ung Sik, Chang, Hak, Lee, Myungsu, Hur, Saebeom, Jae, Hwan Jun, Jung, Chul‐Woo, Yang, Seong‐Mi, Ko, Jae Sung, Lee, Kwang‐Woong, Suh, Kyung‐Suk
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container_end_page 230
container_issue 2
container_start_page 222
container_title Liver transplantation
container_volume 27
creator Ahn, Sung Woo
Yi, Nam‐Joon
Kim, Hyo‐Cheol
Ahn, Hye Young
Hong, Suk Kyun
Lee, Jeong‐Moo
Cho, Jae‐Hyung
Jin, Ung Sik
Chang, Hak
Lee, Myungsu
Hur, Saebeom
Jae, Hwan Jun
Jung, Chul‐Woo
Yang, Seong‐Mi
Ko, Jae Sung
Lee, Kwang‐Woong
Suh, Kyung‐Suk
description The position of the left side liver graft is important, and it could lead to complications of the hepatic vein (HV) and portal vein (PV), especially in a small child using a variant left lateral section (vLLS) graft. The purpose of this study was to evaluate the outcome of a novel technique for the implantation of a vLLS graft to the right side (dextroplantation) in infants. For 3 years, 10 consecutive infants underwent dextroplantation using a vLLS graft (group D). The graft was implanted to the right side of the recipient after 90° counterclockwise rotation; the left HV graft was anastomosed to inferior vena cava using the extended right and middle HV stump, and PV was reconstructed using oblique anastomosis without angulation. Surgical outcomes were compared with the historical control group (n = 17, group C) who underwent conventional liver transplantation using a vLLS during infancy. Group D recipients were smaller than group C (body weight 4% was higher in group D (60.0%) than C (11.8%; P = 0.01). Surgical drains were removed earlier in group D than in group C (15 versus 18 postoperative days [PODs]; P = 0.048). Each group had 1 PV complication (10.0% versus 5.9%); no HV complication occurred in group D, but 3 HV complications (17.6%) occurred in group C (P > 0.05). Hospital stay was shorter in group D than in group C (20 versus 31 PODs; P = 0.02). Dextroplantation of a vLLS graft, even a large‐for‐size one, was successful in small infants without compromising venous outcomes, compared with conventional vLLS transplantation. We could remove the surgical drains earlier and reduce hospital stays in cases of dextroplantation.
doi_str_mv 10.1002/lt.25883
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The purpose of this study was to evaluate the outcome of a novel technique for the implantation of a vLLS graft to the right side (dextroplantation) in infants. For 3 years, 10 consecutive infants underwent dextroplantation using a vLLS graft (group D). The graft was implanted to the right side of the recipient after 90° counterclockwise rotation; the left HV graft was anastomosed to inferior vena cava using the extended right and middle HV stump, and PV was reconstructed using oblique anastomosis without angulation. Surgical outcomes were compared with the historical control group (n = 17, group C) who underwent conventional liver transplantation using a vLLS during infancy. Group D recipients were smaller than group C (body weight &lt;6 kg: 50.0% versus 11.8%; P = 0.03). The rate of graft‐to‐recipient weight ratio &gt;4% was higher in group D (60.0%) than C (11.8%; P = 0.01). Surgical drains were removed earlier in group D than in group C (15 versus 18 postoperative days [PODs]; P = 0.048). Each group had 1 PV complication (10.0% versus 5.9%); no HV complication occurred in group D, but 3 HV complications (17.6%) occurred in group C (P &gt; 0.05). Hospital stay was shorter in group D than in group C (20 versus 31 PODs; P = 0.02). Dextroplantation of a vLLS graft, even a large‐for‐size one, was successful in small infants without compromising venous outcomes, compared with conventional vLLS transplantation. 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The purpose of this study was to evaluate the outcome of a novel technique for the implantation of a vLLS graft to the right side (dextroplantation) in infants. For 3 years, 10 consecutive infants underwent dextroplantation using a vLLS graft (group D). The graft was implanted to the right side of the recipient after 90° counterclockwise rotation; the left HV graft was anastomosed to inferior vena cava using the extended right and middle HV stump, and PV was reconstructed using oblique anastomosis without angulation. Surgical outcomes were compared with the historical control group (n = 17, group C) who underwent conventional liver transplantation using a vLLS during infancy. Group D recipients were smaller than group C (body weight &lt;6 kg: 50.0% versus 11.8%; P = 0.03). The rate of graft‐to‐recipient weight ratio &gt;4% was higher in group D (60.0%) than C (11.8%; P = 0.01). Surgical drains were removed earlier in group D than in group C (15 versus 18 postoperative days [PODs]; P = 0.048). Each group had 1 PV complication (10.0% versus 5.9%); no HV complication occurred in group D, but 3 HV complications (17.6%) occurred in group C (P &gt; 0.05). Hospital stay was shorter in group D than in group C (20 versus 31 PODs; P = 0.02). Dextroplantation of a vLLS graft, even a large‐for‐size one, was successful in small infants without compromising venous outcomes, compared with conventional vLLS transplantation. We could remove the surgical drains earlier and reduce hospital stays in cases of dextroplantation.</abstract><cop>United States</cop><pub>Wolters Kluwer Health, Inc</pub><pmid>32897624</pmid><doi>10.1002/lt.25883</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-0020-6215</orcidid><orcidid>https://orcid.org/0000-0002-9586-8747</orcidid><orcidid>https://orcid.org/0000-0002-5467-425X</orcidid></addata></record>
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source MEDLINE; Wiley Online Library Journals Frontfile Complete; Alma/SFX Local Collection
subjects Anastomosis
Anastomosis, Surgical
Body weight
Child
Hepatic vein
Hepatic Veins - surgery
Humans
Infant
Infants
Liver - diagnostic imaging
Liver - surgery
Liver transplantation
Liver Transplantation - adverse effects
Living Donors
Portal vein
Portal Vein - diagnostic imaging
Portal Vein - surgery
Surgical drains
title Dextroplantation of Left Liver Graft in Infants
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