Dextroplantation of Left Liver Graft in Infants
The position of the left side liver graft is important, and it could lead to complications of the hepatic vein (HV) and portal vein (PV), especially in a small child using a variant left lateral section (vLLS) graft. The purpose of this study was to evaluate the outcome of a novel technique for the...
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Veröffentlicht in: | Liver transplantation 2021-02, Vol.27 (2), p.222-230 |
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creator | Ahn, Sung Woo Yi, Nam‐Joon Kim, Hyo‐Cheol Ahn, Hye Young Hong, Suk Kyun Lee, Jeong‐Moo Cho, Jae‐Hyung Jin, Ung Sik Chang, Hak Lee, Myungsu Hur, Saebeom Jae, Hwan Jun Jung, Chul‐Woo Yang, Seong‐Mi Ko, Jae Sung Lee, Kwang‐Woong Suh, Kyung‐Suk |
description | The position of the left side liver graft is important, and it could lead to complications of the hepatic vein (HV) and portal vein (PV), especially in a small child using a variant left lateral section (vLLS) graft. The purpose of this study was to evaluate the outcome of a novel technique for the implantation of a vLLS graft to the right side (dextroplantation) in infants. For 3 years, 10 consecutive infants underwent dextroplantation using a vLLS graft (group D). The graft was implanted to the right side of the recipient after 90° counterclockwise rotation; the left HV graft was anastomosed to inferior vena cava using the extended right and middle HV stump, and PV was reconstructed using oblique anastomosis without angulation. Surgical outcomes were compared with the historical control group (n = 17, group C) who underwent conventional liver transplantation using a vLLS during infancy. Group D recipients were smaller than group C (body weight 4% was higher in group D (60.0%) than C (11.8%; P = 0.01). Surgical drains were removed earlier in group D than in group C (15 versus 18 postoperative days [PODs]; P = 0.048). Each group had 1 PV complication (10.0% versus 5.9%); no HV complication occurred in group D, but 3 HV complications (17.6%) occurred in group C (P > 0.05). Hospital stay was shorter in group D than in group C (20 versus 31 PODs; P = 0.02). Dextroplantation of a vLLS graft, even a large‐for‐size one, was successful in small infants without compromising venous outcomes, compared with conventional vLLS transplantation. We could remove the surgical drains earlier and reduce hospital stays in cases of dextroplantation. |
doi_str_mv | 10.1002/lt.25883 |
format | Article |
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The purpose of this study was to evaluate the outcome of a novel technique for the implantation of a vLLS graft to the right side (dextroplantation) in infants. For 3 years, 10 consecutive infants underwent dextroplantation using a vLLS graft (group D). The graft was implanted to the right side of the recipient after 90° counterclockwise rotation; the left HV graft was anastomosed to inferior vena cava using the extended right and middle HV stump, and PV was reconstructed using oblique anastomosis without angulation. Surgical outcomes were compared with the historical control group (n = 17, group C) who underwent conventional liver transplantation using a vLLS during infancy. Group D recipients were smaller than group C (body weight <6 kg: 50.0% versus 11.8%; P = 0.03). The rate of graft‐to‐recipient weight ratio >4% was higher in group D (60.0%) than C (11.8%; P = 0.01). Surgical drains were removed earlier in group D than in group C (15 versus 18 postoperative days [PODs]; P = 0.048). Each group had 1 PV complication (10.0% versus 5.9%); no HV complication occurred in group D, but 3 HV complications (17.6%) occurred in group C (P > 0.05). Hospital stay was shorter in group D than in group C (20 versus 31 PODs; P = 0.02). Dextroplantation of a vLLS graft, even a large‐for‐size one, was successful in small infants without compromising venous outcomes, compared with conventional vLLS transplantation. We could remove the surgical drains earlier and reduce hospital stays in cases of dextroplantation.</description><identifier>ISSN: 1527-6465</identifier><identifier>EISSN: 1527-6473</identifier><identifier>DOI: 10.1002/lt.25883</identifier><identifier>PMID: 32897624</identifier><language>eng</language><publisher>United States: Wolters Kluwer Health, Inc</publisher><subject>Anastomosis ; Anastomosis, Surgical ; Body weight ; Child ; Hepatic vein ; Hepatic Veins - surgery ; Humans ; Infant ; Infants ; Liver - diagnostic imaging ; Liver - surgery ; Liver transplantation ; Liver Transplantation - adverse effects ; Living Donors ; Portal vein ; Portal Vein - diagnostic imaging ; Portal Vein - surgery ; Surgical drains</subject><ispartof>Liver transplantation, 2021-02, Vol.27 (2), p.222-230</ispartof><rights>Copyright © 2020 American Association for the Study of Liver Diseases.</rights><rights>Copyright © 2021 by the American Association for the Study of Liver Diseases.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3493-511b5b3f65a4be8f250cfa2b06c55eb1f82966f4bfdf6890389eedc451cc35153</citedby><cites>FETCH-LOGICAL-c3493-511b5b3f65a4be8f250cfa2b06c55eb1f82966f4bfdf6890389eedc451cc35153</cites><orcidid>0000-0002-0020-6215 ; 0000-0002-9586-8747 ; 0000-0002-5467-425X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Flt.25883$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Flt.25883$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32897624$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ahn, Sung Woo</creatorcontrib><creatorcontrib>Yi, Nam‐Joon</creatorcontrib><creatorcontrib>Kim, Hyo‐Cheol</creatorcontrib><creatorcontrib>Ahn, Hye Young</creatorcontrib><creatorcontrib>Hong, Suk Kyun</creatorcontrib><creatorcontrib>Lee, Jeong‐Moo</creatorcontrib><creatorcontrib>Cho, Jae‐Hyung</creatorcontrib><creatorcontrib>Jin, Ung Sik</creatorcontrib><creatorcontrib>Chang, Hak</creatorcontrib><creatorcontrib>Lee, Myungsu</creatorcontrib><creatorcontrib>Hur, Saebeom</creatorcontrib><creatorcontrib>Jae, Hwan Jun</creatorcontrib><creatorcontrib>Jung, Chul‐Woo</creatorcontrib><creatorcontrib>Yang, Seong‐Mi</creatorcontrib><creatorcontrib>Ko, Jae Sung</creatorcontrib><creatorcontrib>Lee, Kwang‐Woong</creatorcontrib><creatorcontrib>Suh, Kyung‐Suk</creatorcontrib><title>Dextroplantation of Left Liver Graft in Infants</title><title>Liver transplantation</title><addtitle>Liver Transpl</addtitle><description>The position of the left side liver graft is important, and it could lead to complications of the hepatic vein (HV) and portal vein (PV), especially in a small child using a variant left lateral section (vLLS) graft. The purpose of this study was to evaluate the outcome of a novel technique for the implantation of a vLLS graft to the right side (dextroplantation) in infants. For 3 years, 10 consecutive infants underwent dextroplantation using a vLLS graft (group D). The graft was implanted to the right side of the recipient after 90° counterclockwise rotation; the left HV graft was anastomosed to inferior vena cava using the extended right and middle HV stump, and PV was reconstructed using oblique anastomosis without angulation. Surgical outcomes were compared with the historical control group (n = 17, group C) who underwent conventional liver transplantation using a vLLS during infancy. Group D recipients were smaller than group C (body weight <6 kg: 50.0% versus 11.8%; P = 0.03). The rate of graft‐to‐recipient weight ratio >4% was higher in group D (60.0%) than C (11.8%; P = 0.01). Surgical drains were removed earlier in group D than in group C (15 versus 18 postoperative days [PODs]; P = 0.048). Each group had 1 PV complication (10.0% versus 5.9%); no HV complication occurred in group D, but 3 HV complications (17.6%) occurred in group C (P > 0.05). Hospital stay was shorter in group D than in group C (20 versus 31 PODs; P = 0.02). Dextroplantation of a vLLS graft, even a large‐for‐size one, was successful in small infants without compromising venous outcomes, compared with conventional vLLS transplantation. We could remove the surgical drains earlier and reduce hospital stays in cases of dextroplantation.</description><subject>Anastomosis</subject><subject>Anastomosis, Surgical</subject><subject>Body weight</subject><subject>Child</subject><subject>Hepatic vein</subject><subject>Hepatic Veins - surgery</subject><subject>Humans</subject><subject>Infant</subject><subject>Infants</subject><subject>Liver - diagnostic imaging</subject><subject>Liver - surgery</subject><subject>Liver transplantation</subject><subject>Liver Transplantation - adverse effects</subject><subject>Living Donors</subject><subject>Portal vein</subject><subject>Portal Vein - diagnostic imaging</subject><subject>Portal Vein - surgery</subject><subject>Surgical drains</subject><issn>1527-6465</issn><issn>1527-6473</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kE1LAzEURYMotlbBXyADbtxMm-_JLKXVWhhwU9chSROYMp2pSUbtvzfaWkRw9e7icLjvAnCN4BhBiCdNHGMmBDkBQ8RwkXNakNNj5mwALkJYQ4gQK-E5GBAsyoJjOgSTmf2Ivts2qo0q1l2bdS6rrItZVb9Zn829Srlus0XrEhIuwZlTTbBXhzsCL48Py-lTXj3PF9P7KjeEliRnCGmmieNMUW2Fwwwap7CG3DBmNXICl5w7qt3KcVFCIkprV4YyZAxhiJERuNt7t7577W2IclMHY5vU03Z9kJhSWEJKCp7Q2z_ouut9m9olSgiWPuW_hMZ3IXjr5NbXG-V3EkH5NaJsovweMaE3B2GvN3Z1BH9WS0C-B97rxu7-FclquRd-As3AeCY</recordid><startdate>202102</startdate><enddate>202102</enddate><creator>Ahn, Sung Woo</creator><creator>Yi, Nam‐Joon</creator><creator>Kim, Hyo‐Cheol</creator><creator>Ahn, Hye Young</creator><creator>Hong, Suk Kyun</creator><creator>Lee, Jeong‐Moo</creator><creator>Cho, Jae‐Hyung</creator><creator>Jin, Ung Sik</creator><creator>Chang, Hak</creator><creator>Lee, Myungsu</creator><creator>Hur, Saebeom</creator><creator>Jae, Hwan Jun</creator><creator>Jung, Chul‐Woo</creator><creator>Yang, Seong‐Mi</creator><creator>Ko, Jae Sung</creator><creator>Lee, Kwang‐Woong</creator><creator>Suh, Kyung‐Suk</creator><general>Wolters Kluwer Health, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-0020-6215</orcidid><orcidid>https://orcid.org/0000-0002-9586-8747</orcidid><orcidid>https://orcid.org/0000-0002-5467-425X</orcidid></search><sort><creationdate>202102</creationdate><title>Dextroplantation of Left Liver Graft in Infants</title><author>Ahn, Sung Woo ; Yi, Nam‐Joon ; Kim, Hyo‐Cheol ; Ahn, Hye Young ; Hong, Suk Kyun ; Lee, Jeong‐Moo ; Cho, Jae‐Hyung ; Jin, Ung Sik ; Chang, Hak ; Lee, Myungsu ; Hur, Saebeom ; Jae, Hwan Jun ; Jung, Chul‐Woo ; Yang, Seong‐Mi ; Ko, Jae Sung ; Lee, Kwang‐Woong ; Suh, Kyung‐Suk</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3493-511b5b3f65a4be8f250cfa2b06c55eb1f82966f4bfdf6890389eedc451cc35153</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Anastomosis</topic><topic>Anastomosis, Surgical</topic><topic>Body weight</topic><topic>Child</topic><topic>Hepatic vein</topic><topic>Hepatic Veins - surgery</topic><topic>Humans</topic><topic>Infant</topic><topic>Infants</topic><topic>Liver - diagnostic imaging</topic><topic>Liver - surgery</topic><topic>Liver transplantation</topic><topic>Liver Transplantation - adverse effects</topic><topic>Living Donors</topic><topic>Portal vein</topic><topic>Portal Vein - diagnostic imaging</topic><topic>Portal Vein - surgery</topic><topic>Surgical drains</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ahn, Sung Woo</creatorcontrib><creatorcontrib>Yi, Nam‐Joon</creatorcontrib><creatorcontrib>Kim, Hyo‐Cheol</creatorcontrib><creatorcontrib>Ahn, Hye Young</creatorcontrib><creatorcontrib>Hong, Suk Kyun</creatorcontrib><creatorcontrib>Lee, Jeong‐Moo</creatorcontrib><creatorcontrib>Cho, Jae‐Hyung</creatorcontrib><creatorcontrib>Jin, Ung Sik</creatorcontrib><creatorcontrib>Chang, Hak</creatorcontrib><creatorcontrib>Lee, Myungsu</creatorcontrib><creatorcontrib>Hur, Saebeom</creatorcontrib><creatorcontrib>Jae, Hwan Jun</creatorcontrib><creatorcontrib>Jung, Chul‐Woo</creatorcontrib><creatorcontrib>Yang, Seong‐Mi</creatorcontrib><creatorcontrib>Ko, Jae Sung</creatorcontrib><creatorcontrib>Lee, Kwang‐Woong</creatorcontrib><creatorcontrib>Suh, Kyung‐Suk</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Liver transplantation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ahn, Sung Woo</au><au>Yi, Nam‐Joon</au><au>Kim, Hyo‐Cheol</au><au>Ahn, Hye Young</au><au>Hong, Suk Kyun</au><au>Lee, Jeong‐Moo</au><au>Cho, Jae‐Hyung</au><au>Jin, Ung Sik</au><au>Chang, Hak</au><au>Lee, Myungsu</au><au>Hur, Saebeom</au><au>Jae, Hwan Jun</au><au>Jung, Chul‐Woo</au><au>Yang, Seong‐Mi</au><au>Ko, Jae Sung</au><au>Lee, Kwang‐Woong</au><au>Suh, Kyung‐Suk</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dextroplantation of Left Liver Graft in Infants</atitle><jtitle>Liver transplantation</jtitle><addtitle>Liver Transpl</addtitle><date>2021-02</date><risdate>2021</risdate><volume>27</volume><issue>2</issue><spage>222</spage><epage>230</epage><pages>222-230</pages><issn>1527-6465</issn><eissn>1527-6473</eissn><abstract>The position of the left side liver graft is important, and it could lead to complications of the hepatic vein (HV) and portal vein (PV), especially in a small child using a variant left lateral section (vLLS) graft. The purpose of this study was to evaluate the outcome of a novel technique for the implantation of a vLLS graft to the right side (dextroplantation) in infants. For 3 years, 10 consecutive infants underwent dextroplantation using a vLLS graft (group D). The graft was implanted to the right side of the recipient after 90° counterclockwise rotation; the left HV graft was anastomosed to inferior vena cava using the extended right and middle HV stump, and PV was reconstructed using oblique anastomosis without angulation. Surgical outcomes were compared with the historical control group (n = 17, group C) who underwent conventional liver transplantation using a vLLS during infancy. Group D recipients were smaller than group C (body weight <6 kg: 50.0% versus 11.8%; P = 0.03). The rate of graft‐to‐recipient weight ratio >4% was higher in group D (60.0%) than C (11.8%; P = 0.01). Surgical drains were removed earlier in group D than in group C (15 versus 18 postoperative days [PODs]; P = 0.048). Each group had 1 PV complication (10.0% versus 5.9%); no HV complication occurred in group D, but 3 HV complications (17.6%) occurred in group C (P > 0.05). Hospital stay was shorter in group D than in group C (20 versus 31 PODs; P = 0.02). Dextroplantation of a vLLS graft, even a large‐for‐size one, was successful in small infants without compromising venous outcomes, compared with conventional vLLS transplantation. We could remove the surgical drains earlier and reduce hospital stays in cases of dextroplantation.</abstract><cop>United States</cop><pub>Wolters Kluwer Health, Inc</pub><pmid>32897624</pmid><doi>10.1002/lt.25883</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-0020-6215</orcidid><orcidid>https://orcid.org/0000-0002-9586-8747</orcidid><orcidid>https://orcid.org/0000-0002-5467-425X</orcidid></addata></record> |
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subjects | Anastomosis Anastomosis, Surgical Body weight Child Hepatic vein Hepatic Veins - surgery Humans Infant Infants Liver - diagnostic imaging Liver - surgery Liver transplantation Liver Transplantation - adverse effects Living Donors Portal vein Portal Vein - diagnostic imaging Portal Vein - surgery Surgical drains |
title | Dextroplantation of Left Liver Graft in Infants |
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