Gas chromatography-mass spectrometry untargeted profiling of non-Hodgkin’s lymphoma urinary metabolite markers

Non-Hodgkin’s lymphoma (NHL) is a cancer of the lymphatic system where the lymphoid and hematopoietic tissues are infiltrated by malignant neoplasms of B, T, and natural killer lymphocytes. Effective and less invasive methods for NHL screening are urgently needed. Herein, we report an untargeted gas...

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2020-11, Vol.412 (27), p.7469-7480
Hauptverfasser:	Bueno Duarte, Gustavo Henrique, de Piloto Fernandes, Anna Maria Alves, Silva, Alex Aparecido Rosini, Zamora-Obando, Hans R., Amaral, Alan Gonçalves, de Sousa Mesquita, Alessandra, Schmidt-Filho, Jayr, Cordeiro de Lima, Vladmir C., D’Almeida Costa, Felipe, Andrade, Victor Piana, Porcari, Andreia M., Eberlin, Marcos Nogueira, Simionato, Ana Valéria Colnaghi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Algorithms Amino acids Analytical Chemistry Biochemistry Biomarkers, Tumor - metabolism Biomarkers, Tumor - urine Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Chromatography Data analysis Female Food Science Gas chromatography Gas Chromatography-Mass Spectrometry - methods Humans Information management Invasiveness Laboratory Medicine Lymphatic system Lymphocytes Lymphocytes T Lymphoma Lymphoma, Non-Hodgkin - metabolism Lymphoma, Non-Hodgkin - urine Male Mass spectrometry Mass spectroscopy Metabolites Metabolome Metabolomics - methods Middle Aged Model accuracy Monitoring/Environmental Analysis Multivariate analysis Neoplasia Neoplasms Non-Hodgkin's lymphoma Non-Hodgkin's lymphomas Organic acids Research Paper Scientific imaging Spectroscopy Spectrum analysis Statistical analysis Statistical methods Sugar Support vector machines Vitamins Volatile compounds
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