The protective effect of piperine against isoproterenol-induced inflammation in experimental models of myocardial toxicity

Myocardial infarction (MI) eventually exacerbates inflammatory response due to the release of inflammatory and pro-inflammatory factors. The aim of this study is to explore the protective efficacy of piperine supplementation against the inflammatory response in isoproterenol (ISO)-induced MI. Masson...

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Veröffentlicht in:	European journal of pharmacology 2020-10, Vol.885, p.173524-173524, Article 173524
Hauptverfasser:	Viswanadha, Vijaya Padma, Dhivya, Velumani, Beeraka, Narasimha Murthy, Huang, Chih-Yang, Gavryushova, Liliya V., Minyaeva, Nina N., Chubarev, Vladimir N., Mikhaleva, Liudmila M., Tarasov, Vadim V., Aliev, Gjumrakch
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Agonists - toxicity Alkaloids - pharmacology Animals Benzodioxoles - pharmacology Cardiomegaly - prevention & control Cytokines - metabolism Endothelium - pathology Experimental cardiac toxicity Fibrosis Gene expressions Inflammation - chemically induced Inflammation - genetics Inflammation - prevention & control Isoproterenol - antagonists & inhibitors Isoproterenol - toxicity Isoproterenol and inflammation Male Myocardial Infarction - chemically induced Myocardial Infarction - prevention & control Myocardial toxicity Myocardium - pathology NF-κB Piperidines - pharmacology Piperine as a protective agent Polyunsaturated Alkamides - pharmacology Rats Rats, Wistar Signal Transduction - drug effects Transcription Factor RelA - antagonists & inhibitors Transcription Factor RelA - biosynthesis
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