Novel antibiotic-loaded particles conferring eradication of deep tissue bacterial reservoirs for the treatment of chronic urinary tract infection

A significant proportion of urinary tract infection (UTI) patients experience recurrent episodes, due to deep tissue infection and treatment-resistant bacterial reservoirs. Direct bladder instillation of antibiotics has proved disappointing in treating UTI, likely due to the failure of infused antib...

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Veröffentlicht in:	Journal of controlled release 2020-12, Vol.328, p.490-502
Hauptverfasser:	Lau, Wai K., Dharmasena, Dhanuson, Horsley, Harry, Jafari, Nazila V., Malone-Lee, James, Stride, Eleanor, Edirisinghe, Mohan, Rohn, Jennifer L.
Format:	Artikel
Sprache:	eng
Schlagworte:	3D organoid Antimicrobial resistance Electrospray Intracellular drug delivery Urinary tract infection
Online-Zugang:	Volltext
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