Sex differences in the coagulation process and microvascular perfusion induced by brain death in rats

Summary Brain death (BD) leads to a systemic inflammation associated with the activation of coagulation, which could be related to decreased microcirculatory perfusion. Evidence shows that females exhibit higher platelet aggregability than males. Thus, we investigated sex differences in platelets, c...

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Veröffentlicht in:	Transplant international 2020-11, Vol.33 (11), p.1541-1550
Hauptverfasser:	Correia, Cristiano de Jesus, Ricardo da Silva, Fernanda Yamamoto, Armstrong, Roberto, Vidal dos Santos, Marina, Anunciação, Lucas Ferreira, Sobral, Marcelo Luiz Peixoto, Coutinho e Silva, Raphael dos Santos, Leuvenink, Hendrik Gerrit Derk, Breithaupt‐Faloppa, Ana Cristina, Moreira, Luiz Felipe Pinho
Format:	Artikel
Sprache:	eng
Schlagworte:	Agglomeration Brain Brain death Clotting Coagulation Dimorphism Estrus cycle Females Gender aspects Gender differences Inflammation Inflammatory response Leukocytes Males Microvasculature organ donor Perfusion Platelet aggregation Platelets rat Reduction Rodents Sex Sex differences Sexual dimorphism tromboelastometry
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