In vitro and in vivo evaluation of structurally-controlled silk fibroin coatings for orthopedic infection and in-situ osteogenesis

Biomedical device-associated infections (BAI) and osteosynthesis are two main complications following the orthopedic implant surgery, especially while infecting bacteria form a mature biofilm, which can protect the organisms from the host immune system and antibiotic therapy. Comparing with the sing...

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Veröffentlicht in:Acta biomaterialia 2020-10, Vol.116, p.223-245
Hauptverfasser: Wenhao, Zhou, Zhang, Teng, Yan, Jianglong, Li, QiYao, Xiong, Panpan, Li, Yangyang, Cheng, Yan, Zheng, Yufeng
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Sprache:eng
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