Peculiarities of the Functional State of Mitochondria of Peripheral Blood Leukocytes in Patients with Acute Myocardial Infarction

We studied the rate of oxygen consumption by mitochondria isolated from peripheral blood leukocytes of patients with acute myocardial infarction and healthy volunteers. It was found that leukocyte mitochondria in patients with acute myocardial infarction were characterized by significantly lower rat...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2020-08, Vol.169 (4), p.435-437
Hauptverfasser: Afanas’ev, S. А., Muslimova, E. F., Rebrova, Т. Yu, Tsapko, L. P., Kercheva, М. А., Golubenko, М. V.
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container_end_page 437
container_issue 4
container_start_page 435
container_title Bulletin of experimental biology and medicine
container_volume 169
creator Afanas’ev, S. А.
Muslimova, E. F.
Rebrova, Т. Yu
Tsapko, L. P.
Kercheva, М. А.
Golubenko, М. V.
description We studied the rate of oxygen consumption by mitochondria isolated from peripheral blood leukocytes of patients with acute myocardial infarction and healthy volunteers. It was found that leukocyte mitochondria in patients with acute myocardial infarction were characterized by significantly lower rate of oxygen consumption and lower level of coupling of oxidation and phosphorylation processes in comparison with mitochondria from healthy volunteers.
doi_str_mv 10.1007/s10517-020-04903-9
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subjects Biomedical and Life Sciences
Biomedicine
Cardiac patients
Cell Biology
Ethylenediaminetetraacetic acid
Heart attack
Internal Medicine
Laboratory Medicine
Pathology
Physiological aspects
title Peculiarities of the Functional State of Mitochondria of Peripheral Blood Leukocytes in Patients with Acute Myocardial Infarction
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