A class of low‐cost alternatives to kifunensine for increasing high mannose N‐linked glycosylation for monoclonal antibody production in Chinese hamster ovary cells

N‐linked glycosylation of therapeutic monoclonal antibodies is an important product quality attribute for drug safety and efficacy. An increase in the percent of high mannose N‐linked glycosylation may be required for drug efficacy or to match the glycosylation profile of the innovator drug during t...

Ausführliche Beschreibung