Serum IgG4 Subclass Deficiency Defines a Distinct, Commonly Encountered, Severe Inflammatory Bowel Disease Subtype

Abstract Background Immunoglobulin G subclass 4 (IgG4) is hypothesized to play an immunomodulatory role, downregulating humoral immune responses. The role of this anti-inflammatory molecule in inflammatory bowel disease (IBD) has not been fully characterized. We sought to define alterations in serum...

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Veröffentlicht in:	Inflammatory bowel diseases 2021-05, Vol.27 (6), p.855-863
Hauptverfasser:	Koutroumpakis, Filippos, Phillips, Anna Evans, Yadav, Dhiraj, Machicado, Jorge D, Ahsan, Maaz, Ramos Rivers, Claudia, Tan, Xiaoqing, Schwartz, Marc, Proksell, Siobhan, Johnston, Elyse, Dueker, Jeffrey, Hashash, Jana G, Barrie, Arthur, Harrison, Janet, Dunn, Michael A, Konnikova, Liza, Hartman, Douglas J, Din, Hasieb, Babichenko, Dmitriy, Tang, Gong, Binion, David G
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Cholangitis, Sclerosing - diagnosis Cholangitis, Sclerosing - immunology Humans Immunoglobulin G - blood Inflammatory Bowel Diseases - diagnosis Inflammatory Bowel Diseases - immunology
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