Structural biology of plant defence
Plants employ the innate immune system to discriminate between self and invaders through two types of immune receptors, one on the plas mamembrane and the other in the intracellular space. The immune receptors on the plasma membrane are pattern recognition receptors (PRRs) that can perceive pathogen...
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| Veröffentlicht in: | The New phytologist 2021-01, Vol.229 (2), p.692-711 |
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| container_end_page | 711 |
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| container_title | The New phytologist |
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| creator | Song, Wen Forderer, Alexander Yu, Dongli Chai, Jijie |
| description | Plants employ the innate immune system to discriminate between self and invaders through two types of immune receptors, one on the plas mamembrane and the other in the intracellular space. The immune receptors on the plasma membrane are pattern recognition receptors (PRRs) that can perceive pathogen-associated molecular patterns (PAMPs) or host-derived damage-associated molecular patterns (DAMPs) leading to pattern-triggered immunity (PTI). Particular pathogens are capable of overcoming PTI by secreting specific effectors into plant cells to perturb different components of PTI signalling through various mechanisms. Most of the immune receptors from the intracellular space are the nucleotide-binding leucine-rich repeat receptors (NLRs), which specifically recognize pathogen-secreted effectors to mediate effector-triggered immunity (ETI). In this review, we will summarize recent progress in structural studies of PRRs, NLRs, and effectors, and discuss how these studies shed light on ligand recognition and activation mechanisms of the two types of immune receptors and the diversified mechanisms used by effectors to manipulate plant immune signalling. |
| doi_str_mv | 10.1111/nph.16906 |
| format | Article |
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The immune receptors on the plasma membrane are pattern recognition receptors (PRRs) that can perceive pathogen-associated molecular patterns (PAMPs) or host-derived damage-associated molecular patterns (DAMPs) leading to pattern-triggered immunity (PTI). Particular pathogens are capable of overcoming PTI by secreting specific effectors into plant cells to perturb different components of PTI signalling through various mechanisms. Most of the immune receptors from the intracellular space are the nucleotide-binding leucine-rich repeat receptors (NLRs), which specifically recognize pathogen-secreted effectors to mediate effector-triggered immunity (ETI). In this review, we will summarize recent progress in structural studies of PRRs, NLRs, and effectors, and discuss how these studies shed light on ligand recognition and activation mechanisms of the two types of immune receptors and the diversified mechanisms used by effectors to manipulate plant immune signalling.</description><identifier>ISSN: 0028-646X</identifier><identifier>EISSN: 1469-8137</identifier><identifier>DOI: 10.1111/nph.16906</identifier><identifier>PMID: 32880948</identifier><language>eng</language><publisher>England: Wiley</publisher><subject>Biology ; Damage patterns ; Effectors ; Immune system ; Immunity ; Innate immunity ; Intracellular ; Intracellular signalling ; Leucine ; Membranes ; Nucleotides ; nucleotide‐binding leucine‐rich repeat receptors ; Pathogen-Associated Molecular Pattern Molecules ; Pathogens ; Pattern recognition ; Pattern recognition receptors ; Plant cells ; Plant Diseases ; Plant Immunity ; Plants ; Receptors ; Receptors, Pattern Recognition ; Signaling ; structural biology ; Tansley review</subject><ispartof>The New phytologist, 2021-01, Vol.229 (2), p.692-711</ispartof><rights>2020 The Authors © 2020 New Phytologist Foundation</rights><rights>2020 The Authors New Phytologist © 2020 New Phytologist Trust</rights><rights>2020 The Authors New Phytologist © 2020 New Phytologist Trust.</rights><rights>2020. This article is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). 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The immune receptors on the plasma membrane are pattern recognition receptors (PRRs) that can perceive pathogen-associated molecular patterns (PAMPs) or host-derived damage-associated molecular patterns (DAMPs) leading to pattern-triggered immunity (PTI). Particular pathogens are capable of overcoming PTI by secreting specific effectors into plant cells to perturb different components of PTI signalling through various mechanisms. Most of the immune receptors from the intracellular space are the nucleotide-binding leucine-rich repeat receptors (NLRs), which specifically recognize pathogen-secreted effectors to mediate effector-triggered immunity (ETI). 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The immune receptors on the plasma membrane are pattern recognition receptors (PRRs) that can perceive pathogen-associated molecular patterns (PAMPs) or host-derived damage-associated molecular patterns (DAMPs) leading to pattern-triggered immunity (PTI). Particular pathogens are capable of overcoming PTI by secreting specific effectors into plant cells to perturb different components of PTI signalling through various mechanisms. Most of the immune receptors from the intracellular space are the nucleotide-binding leucine-rich repeat receptors (NLRs), which specifically recognize pathogen-secreted effectors to mediate effector-triggered immunity (ETI). 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| subjects | Biology Damage patterns Effectors Immune system Immunity Innate immunity Intracellular Intracellular signalling Leucine Membranes Nucleotides nucleotide‐binding leucine‐rich repeat receptors Pathogen-Associated Molecular Pattern Molecules Pathogens Pattern recognition Pattern recognition receptors Plant cells Plant Diseases Plant Immunity Plants Receptors Receptors, Pattern Recognition Signaling structural biology Tansley review |
| title | Structural biology of plant defence |
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