Noninvasive inferring expressed genes and in vivo monitoring of the physiology and pathology of pregnancy using cell-free DNA

Noninvasive monitoring of fetal development and the early detection of pregnancy-associated complications is challenging, largely because of the lack of information about the molecular spectrum during pregnancy. Recently, cell-free DNA in plasma was found to reflect the global nucleosome footprint a...

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Veröffentlicht in:	American journal of obstetrics and gynecology 2021-03, Vol.224 (3), p.300.e1-300.e9
Hauptverfasser:	Han, Bo-Wei, Yang, Fang, Guo, Zhi-Wei, Ouyang, Guo-Jun, Liang, Zhi-Kun, Weng, Rong-Tao, Yang, Xu, Huang, Li-Ping, Wang, Ke, Li, Fen-Xia, Huang, Jie, Yang, Xue-Xi, Wu, Ying-Song
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult cell-free DNA Female Gene Expression Humans Middle Aged Noninvasive Prenatal Testing nucleosome footprint Pregnancy Pregnancy Complications - blood Pregnancy Complications - genetics Proof of Concept Study whole genome sequencing Young Adult
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