Long noncoding RNA PWRN1 is lowly expressed in osteosarcoma and modulates cancer proliferation and migration by targeting hsa‐miR‐214‐5p

Background We examined the expression pattern, clinical relevance, and molecular mechanisms of lncRNA PWRN1 in human osteosarcoma. Methods qPCR was used to measure PWRN1 expressions in cell lines and tumor samples osteosarcoma. The correlations between PWRN1 and cancer patients' clinicopatholog...

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Veröffentlicht in:	IUBMB life 2020-11, Vol.72 (11), p.2444-2453
Hauptverfasser:	Shi, Jiyuan, Fu, Qiang, Yang, Pei, Yi, Zhi, Liu, Shizhang, Wang, Kunzheng
Format:	Artikel
Sprache:	eng
Schlagworte:	biomarker Bone cancer Cancer Cell growth Cell proliferation Chemoresistance Cisplatin Epigenetics lncRNA Medical prognosis Metastases miRNA miR‐214 Molecular modelling Osteosarcoma Osteosarcoma cells Precision medicine PWRN1 Ribonucleic acid RNA Tumor cell lines Xenografts
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