Key transporters leading to specific protoporphyrin IX accumulation in cancer cell following administration of aminolevulinic acid in photodynamic therapy/diagnosis

The administration of aminolevulinic acid allow the formation and accumulation of protoporphyrin IX specifically in cancer cells, which then lead to photocytotoxicity following light irradiation. This compound, when accumulated at high levels, could also be used in cancer diagnosis as it would emit...

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Veröffentlicht in:International journal of clinical oncology 2021-01, Vol.26 (1), p.26-33
Hauptverfasser: Lai, Hung Wei, Nakayama, Taku, Ogura, Shun-ichiro
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Sprache:eng
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