Peptides from Extruded Lupin (Lupinus albus L.) Regulate Inflammatory Activity via the p38 MAPK Signal Transduction Pathway in RAW 264.7 Cells

In this study, protein was extracted from extruded lupin and submitted to gastroduodenal digests to obtain lupin peptides, which were characterized using ultraperformance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS). After this, IQDKEGIPPDQQR (IQD), the lupine peptide monomer characte...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2020-10, Vol.68 (42), p.11702-11709
Hauptverfasser:	Gao, Yue, Zhang, Xuna, Ren, Guixing, Wu, Caie, Qin, Peiyou, Yao, Yang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology Bioactive Constituents, Metabolites, and Functions Inflammation - genetics Inflammation - immunology Lupinus - chemistry Macrophages - drug effects Macrophages - immunology Mice p38 Mitogen-Activated Protein Kinases - genetics p38 Mitogen-Activated Protein Kinases - immunology Peptides - pharmacology Plant Proteins - chemistry RAW 264.7 Cells Seeds - chemistry Tandem Mass Spectrometry
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