Application of microfluidic devices for glioblastoma study: current status and future directions

Glioblastoma (GBM) is one of the most malignant primary brain tumors. This neoplasm is the hardest to treat and has a bad prognosis. Because of the characteristics of genetic heterogeneity and frequent recurrence, a successful cure for the disease is unlikely. Increasing evidence has revealed that t...

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Veröffentlicht in:	Biomedical microdevices 2020-09, Vol.22 (3), p.60, Article 60
Hauptverfasser:	Cai, Xue, Briggs, Robert G., Homburg, Hannah B., Young, Isabella M., Davis, Ethan J., Lin, Yueh-Hsin, Battiste, James D., Sughrue, Michael E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and Medical Physics Biomedical Engineering and Bioengineering Biophysics Brain Brain cancer Brain Neoplasms - pathology Brain Neoplasms - therapy Brain tumors Correlation analysis Engineering Engineering Fluid Dynamics Glioblastoma Glioblastoma - metabolism Glioblastoma - pathology Heterogeneity Humans Lab-On-A-Chip Devices Malignancy Microfluidic devices Microfluidics Mimicry Nanotechnology Neoplastic Stem Cells - metabolism Neoplastic Stem Cells - pathology Stem cells System effectiveness Tumor Microenvironment Tumors
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