Kinetics of leukemic cells in 3D culture with stromal cells and with arginine deprivation stress

Previously, we established a three-dimensional (3D) bone marrow culture system that maintains normal hematopoiesis, including prolongation of hematopoietic stem cell proliferation and differentiation. To analyze the role of bone marrow stromal cells that compose the microenvironment, the growth of a...

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Veröffentlicht in:Journal of bioscience and bioengineering 2020-12, Vol.130 (6), p.650-658
Hauptverfasser: Harada, Tomonori, Tsuboi, Isao, Utsunomiya, Mizuki, Yasuda, Masahiro, Aizawa, Shin
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Sprache:eng
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