Recognition of nucleolin through interaction with RNA G-quadruplex

[Display omitted] The development of novel biomarkers for early-stage diagnosis of prostate cancer (PCa) has attracted the attention of researchers in the last decade. Nucleolin (NCL) has emerged as a possible biomarker of PCa due to its high expression levels in the surface of PCa cells and affinit...

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Veröffentlicht in:	Biochemical pharmacology 2021-07, Vol.189, p.114208-114208, Article 114208
Hauptverfasser:	Santos, Tiago, Miranda, André, Campello, Maria P.C., Paulo, António, Salgado, Gilmar, Cabrita, Eurico J., Cruz, Carla
Format:	Artikel
Sprache:	eng
Schlagworte:	Acridine ligands G-Quadruplexes Humans Microfluidic Analytical Techniques - methods Microfluidics and Prostate cancer MicroRNAs - chemistry MicroRNAs - metabolism Molecular Docking Simulation - methods Nucleolin Phosphoproteins - chemistry Phosphoproteins - metabolism Protein Binding - physiology Protein Structure, Secondary RNA G-quadruplex RNA-Binding Proteins - chemistry RNA-Binding Proteins - metabolism
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