Monitoring Arteriovenous Malformation Response to Genotype-Targeted Therapy

Arteriovenous malformations (AVMs) have recently been reported to have a high incidence of somatic KRAS mutations suggesting potential for treatment with mitogen-activated protein kinase inhibitors. In this case report, we describe genotype-targeted treatment of a KRAS mutant metameric AVM in a pati...

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Veröffentlicht in:	Pediatrics (Evanston) 2020-09, Vol.146 (3), p.1
Hauptverfasser:	Edwards, Emily A., Phelps, Andrew S., Cooke, Daniel, Frieden, Ilona J., Zapala, Matthew A., Fullerton, Heather J., Shimano, Kristin A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiography Blood flow Enzyme inhibitors Genotypes K-Ras protein Kinases MAP kinase Pediatrics Protein kinase inhibitors
Online-Zugang:	Volltext
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