The role of the mTOR pathway in models of drug-induced reward and the behavioural constituents of addiction

Background: Exposure to drugs of abuse induces neuroadaptations in critical nodes of the so-called reward systems that are thought to mediate the transition from controlled drug use to the compulsive drug-seeking that characterizes addictive disorders. These neural adaptations are likely to require...

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Veröffentlicht in:	Journal of Psychopharmacology 2020-11, Vol.34 (11), p.1176-1199
Hauptverfasser:	Ucha, Marcos, Roura-Martínez, David, Ambrosio, Emilio, Higuera-Matas, Alejandro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation Addictions Animal models Drug abuse Drug addiction Drugs Impulsive behavior Literature reviews Opioids Protein biosynthesis Rapamycin Reinforcement Signal transduction TOR protein
Online-Zugang:	Volltext
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