Impact of Red Yeast Rice on Metabolic Diseases: A Review of Possible Mechanisms of Action
Metabolic diseases constitute a major public health burden and are linked with high morbidity and mortality. They comprise atherosclerosis dyslipidemia, diabetes, hypertension, and obesity. However, there is no single drug that can simultaneously treat multiple diseases with complex underlying mecha...
Gespeichert in:
| Veröffentlicht in: | Journal of agricultural and food chemistry 2020-09, Vol.68 (39), p.10441-10455 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 10455 |
|---|---|
| container_issue | 39 |
| container_start_page | 10441 |
| container_title | Journal of agricultural and food chemistry |
| container_volume | 68 |
| creator | Hu, Ju Wang, Jin Gan, Qing-xia Ran, Qian Lou, Guan-hua Xiong, Hai-jun Peng, Cheng-yi Sun, Ji-lin Yao, Ren-chuan Huang, Qin-wan |
| description | Metabolic diseases constitute a major public health burden and are linked with high morbidity and mortality. They comprise atherosclerosis dyslipidemia, diabetes, hypertension, and obesity. However, there is no single drug that can simultaneously treat multiple diseases with complex underlying mechanisms. Therefore, it is necessary to identify a class of adjuvant drugs that block the development of metabolic diseases from a preventive perspective. Red yeast rice is a food fermentation product widely used to promote blood circulation and remove blood stasis. Modern pharmacology has shown that red yeast rice exerts potential protective effects on the liver, pancreas, blood vessels, and intestines. Therefore, this study was carried out to analyze and summarize the effect of red yeast rice on several metabolic diseases and the mechanisms of action involved. It was found that red yeast rice may be beneficial in the prevention and treatment of metabolic diseases. |
| doi_str_mv | 10.1021/acs.jafc.0c01893 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2438676682</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2438676682</sourcerecordid><originalsourceid>FETCH-LOGICAL-a336t-45be03f68bd287de57a00324a8a91383fbca152090e3e1d5b148586e20f7506e3</originalsourceid><addsrcrecordid>eNp1kD1PwzAQhi0EoqWwM6GMDKSc4zhx2KryVQkEqmDoZDnORbhK4hInIP49Di1sTJbOz_vq7iHklMKUQkQvlXbTtSr1FDRQkbE9MqY8gpBTKvbJGDwTCp7QETlybg0AgqdwSEYsEjyOs2xMVot6o3QX2DJYYhGsULkuWBqNgW2CR-xUbiujg2vj_A-6q2DmuQ-Dn0Pi2Tpn8go9qN9UY1zthvFMd8Y2x-SgVJXDk907Ia-3Ny_z-_Dh6W4xnz2EirGkC2OeI7AyEXkRibRAnioAFsVKqIwywcpcq-GmDJAhLXhOY8FFghGUKYcE2YScb3s3rX3v0XWyNk5jVakGbe9kFDORpEkiIo_CFtWt37zFUm5aU6v2S1KQg1DphcpBqNwJ9ZGzXXuf11j8BX4NeuBiC_xEbd82_tj_-74B_ex_oA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2438676682</pqid></control><display><type>article</type><title>Impact of Red Yeast Rice on Metabolic Diseases: A Review of Possible Mechanisms of Action</title><source>MEDLINE</source><source>ACS Publications</source><creator>Hu, Ju ; Wang, Jin ; Gan, Qing-xia ; Ran, Qian ; Lou, Guan-hua ; Xiong, Hai-jun ; Peng, Cheng-yi ; Sun, Ji-lin ; Yao, Ren-chuan ; Huang, Qin-wan</creator><creatorcontrib>Hu, Ju ; Wang, Jin ; Gan, Qing-xia ; Ran, Qian ; Lou, Guan-hua ; Xiong, Hai-jun ; Peng, Cheng-yi ; Sun, Ji-lin ; Yao, Ren-chuan ; Huang, Qin-wan</creatorcontrib><description>Metabolic diseases constitute a major public health burden and are linked with high morbidity and mortality. They comprise atherosclerosis dyslipidemia, diabetes, hypertension, and obesity. However, there is no single drug that can simultaneously treat multiple diseases with complex underlying mechanisms. Therefore, it is necessary to identify a class of adjuvant drugs that block the development of metabolic diseases from a preventive perspective. Red yeast rice is a food fermentation product widely used to promote blood circulation and remove blood stasis. Modern pharmacology has shown that red yeast rice exerts potential protective effects on the liver, pancreas, blood vessels, and intestines. Therefore, this study was carried out to analyze and summarize the effect of red yeast rice on several metabolic diseases and the mechanisms of action involved. It was found that red yeast rice may be beneficial in the prevention and treatment of metabolic diseases.</description><identifier>ISSN: 0021-8561</identifier><identifier>EISSN: 1520-5118</identifier><identifier>DOI: 10.1021/acs.jafc.0c01893</identifier><identifier>PMID: 32854499</identifier><language>eng</language><publisher>United States: American Chemical Society</publisher><subject>Animals ; Biological Products - administration & dosage ; Dietary Supplements - analysis ; Humans ; Metabolic Diseases - drug therapy ; Metabolic Diseases - metabolism</subject><ispartof>Journal of agricultural and food chemistry, 2020-09, Vol.68 (39), p.10441-10455</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a336t-45be03f68bd287de57a00324a8a91383fbca152090e3e1d5b148586e20f7506e3</citedby><cites>FETCH-LOGICAL-a336t-45be03f68bd287de57a00324a8a91383fbca152090e3e1d5b148586e20f7506e3</cites><orcidid>0000-0002-6071-051X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/acs.jafc.0c01893$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/acs.jafc.0c01893$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>314,778,782,2754,27059,27907,27908,56721,56771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32854499$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hu, Ju</creatorcontrib><creatorcontrib>Wang, Jin</creatorcontrib><creatorcontrib>Gan, Qing-xia</creatorcontrib><creatorcontrib>Ran, Qian</creatorcontrib><creatorcontrib>Lou, Guan-hua</creatorcontrib><creatorcontrib>Xiong, Hai-jun</creatorcontrib><creatorcontrib>Peng, Cheng-yi</creatorcontrib><creatorcontrib>Sun, Ji-lin</creatorcontrib><creatorcontrib>Yao, Ren-chuan</creatorcontrib><creatorcontrib>Huang, Qin-wan</creatorcontrib><title>Impact of Red Yeast Rice on Metabolic Diseases: A Review of Possible Mechanisms of Action</title><title>Journal of agricultural and food chemistry</title><addtitle>J. Agric. Food Chem</addtitle><description>Metabolic diseases constitute a major public health burden and are linked with high morbidity and mortality. They comprise atherosclerosis dyslipidemia, diabetes, hypertension, and obesity. However, there is no single drug that can simultaneously treat multiple diseases with complex underlying mechanisms. Therefore, it is necessary to identify a class of adjuvant drugs that block the development of metabolic diseases from a preventive perspective. Red yeast rice is a food fermentation product widely used to promote blood circulation and remove blood stasis. Modern pharmacology has shown that red yeast rice exerts potential protective effects on the liver, pancreas, blood vessels, and intestines. Therefore, this study was carried out to analyze and summarize the effect of red yeast rice on several metabolic diseases and the mechanisms of action involved. It was found that red yeast rice may be beneficial in the prevention and treatment of metabolic diseases.</description><subject>Animals</subject><subject>Biological Products - administration & dosage</subject><subject>Dietary Supplements - analysis</subject><subject>Humans</subject><subject>Metabolic Diseases - drug therapy</subject><subject>Metabolic Diseases - metabolism</subject><issn>0021-8561</issn><issn>1520-5118</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kD1PwzAQhi0EoqWwM6GMDKSc4zhx2KryVQkEqmDoZDnORbhK4hInIP49Di1sTJbOz_vq7iHklMKUQkQvlXbTtSr1FDRQkbE9MqY8gpBTKvbJGDwTCp7QETlybg0AgqdwSEYsEjyOs2xMVot6o3QX2DJYYhGsULkuWBqNgW2CR-xUbiujg2vj_A-6q2DmuQ-Dn0Pi2Tpn8go9qN9UY1zthvFMd8Y2x-SgVJXDk907Ia-3Ny_z-_Dh6W4xnz2EirGkC2OeI7AyEXkRibRAnioAFsVKqIwywcpcq-GmDJAhLXhOY8FFghGUKYcE2YScb3s3rX3v0XWyNk5jVakGbe9kFDORpEkiIo_CFtWt37zFUm5aU6v2S1KQg1DphcpBqNwJ9ZGzXXuf11j8BX4NeuBiC_xEbd82_tj_-74B_ex_oA</recordid><startdate>20200930</startdate><enddate>20200930</enddate><creator>Hu, Ju</creator><creator>Wang, Jin</creator><creator>Gan, Qing-xia</creator><creator>Ran, Qian</creator><creator>Lou, Guan-hua</creator><creator>Xiong, Hai-jun</creator><creator>Peng, Cheng-yi</creator><creator>Sun, Ji-lin</creator><creator>Yao, Ren-chuan</creator><creator>Huang, Qin-wan</creator><general>American Chemical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-6071-051X</orcidid></search><sort><creationdate>20200930</creationdate><title>Impact of Red Yeast Rice on Metabolic Diseases: A Review of Possible Mechanisms of Action</title><author>Hu, Ju ; Wang, Jin ; Gan, Qing-xia ; Ran, Qian ; Lou, Guan-hua ; Xiong, Hai-jun ; Peng, Cheng-yi ; Sun, Ji-lin ; Yao, Ren-chuan ; Huang, Qin-wan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a336t-45be03f68bd287de57a00324a8a91383fbca152090e3e1d5b148586e20f7506e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Animals</topic><topic>Biological Products - administration & dosage</topic><topic>Dietary Supplements - analysis</topic><topic>Humans</topic><topic>Metabolic Diseases - drug therapy</topic><topic>Metabolic Diseases - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hu, Ju</creatorcontrib><creatorcontrib>Wang, Jin</creatorcontrib><creatorcontrib>Gan, Qing-xia</creatorcontrib><creatorcontrib>Ran, Qian</creatorcontrib><creatorcontrib>Lou, Guan-hua</creatorcontrib><creatorcontrib>Xiong, Hai-jun</creatorcontrib><creatorcontrib>Peng, Cheng-yi</creatorcontrib><creatorcontrib>Sun, Ji-lin</creatorcontrib><creatorcontrib>Yao, Ren-chuan</creatorcontrib><creatorcontrib>Huang, Qin-wan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of agricultural and food chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hu, Ju</au><au>Wang, Jin</au><au>Gan, Qing-xia</au><au>Ran, Qian</au><au>Lou, Guan-hua</au><au>Xiong, Hai-jun</au><au>Peng, Cheng-yi</au><au>Sun, Ji-lin</au><au>Yao, Ren-chuan</au><au>Huang, Qin-wan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Impact of Red Yeast Rice on Metabolic Diseases: A Review of Possible Mechanisms of Action</atitle><jtitle>Journal of agricultural and food chemistry</jtitle><addtitle>J. Agric. Food Chem</addtitle><date>2020-09-30</date><risdate>2020</risdate><volume>68</volume><issue>39</issue><spage>10441</spage><epage>10455</epage><pages>10441-10455</pages><issn>0021-8561</issn><eissn>1520-5118</eissn><abstract>Metabolic diseases constitute a major public health burden and are linked with high morbidity and mortality. They comprise atherosclerosis dyslipidemia, diabetes, hypertension, and obesity. However, there is no single drug that can simultaneously treat multiple diseases with complex underlying mechanisms. Therefore, it is necessary to identify a class of adjuvant drugs that block the development of metabolic diseases from a preventive perspective. Red yeast rice is a food fermentation product widely used to promote blood circulation and remove blood stasis. Modern pharmacology has shown that red yeast rice exerts potential protective effects on the liver, pancreas, blood vessels, and intestines. Therefore, this study was carried out to analyze and summarize the effect of red yeast rice on several metabolic diseases and the mechanisms of action involved. It was found that red yeast rice may be beneficial in the prevention and treatment of metabolic diseases.</abstract><cop>United States</cop><pub>American Chemical Society</pub><pmid>32854499</pmid><doi>10.1021/acs.jafc.0c01893</doi><tpages>15</tpages><orcidid>https://orcid.org/0000-0002-6071-051X</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0021-8561 |
| ispartof | Journal of agricultural and food chemistry, 2020-09, Vol.68 (39), p.10441-10455 |
| issn | 0021-8561 1520-5118 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2438676682 |
| source | MEDLINE; ACS Publications |
| subjects | Animals Biological Products - administration & dosage Dietary Supplements - analysis Humans Metabolic Diseases - drug therapy Metabolic Diseases - metabolism |
| title | Impact of Red Yeast Rice on Metabolic Diseases: A Review of Possible Mechanisms of Action |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T09%3A30%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Impact%20of%20Red%20Yeast%20Rice%20on%20Metabolic%20Diseases:%20A%20Review%20of%20Possible%20Mechanisms%20of%20Action&rft.jtitle=Journal%20of%20agricultural%20and%20food%20chemistry&rft.au=Hu,%20Ju&rft.date=2020-09-30&rft.volume=68&rft.issue=39&rft.spage=10441&rft.epage=10455&rft.pages=10441-10455&rft.issn=0021-8561&rft.eissn=1520-5118&rft_id=info:doi/10.1021/acs.jafc.0c01893&rft_dat=%3Cproquest_cross%3E2438676682%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2438676682&rft_id=info:pmid/32854499&rfr_iscdi=true |