African Americans now outpace whites in opioid‐involved overdose deaths: a comparison of temporal trends from 1999 to 2018

Aims To estimate racial differences in rates of opioid‐involved overdose deaths (OOD) between whites and African Americans in the United States from 1999 to 2018 to (1) identify racial variation in the temporal trends of OOD during the 20‐year period and (2) compare trends in OOD rates between white...

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Veröffentlicht in:Addiction (Abingdon, England) England), 2021-03, Vol.116 (3), p.677-683
Hauptverfasser: Furr‐Holden, Debra, Milam, Adam J., Wang, Ling, Sadler, Richard
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creator Furr‐Holden, Debra
Milam, Adam J.
Wang, Ling
Sadler, Richard
description Aims To estimate racial differences in rates of opioid‐involved overdose deaths (OOD) between whites and African Americans in the United States from 1999 to 2018 to (1) identify racial variation in the temporal trends of OOD during the 20‐year period and (2) compare trends in OOD rates between whites and African Americans using the Centers for Disease Control and Prevention's (CDC) three defined OOD epidemic periods. Methods Data were obtained from the CDC wide‐ranging on‐line data for epidemiological research, which combines OOD data from the National Vital Statistics System, and population data from the US Census Bureau. Joinpoint regression models were used to estimate age‐adjusted annual percentage change (APC) in OOD by race from 1999 to 2018. Results The temporal trends of OOD varied by race. African Americans had a persistently low rate of OOD and statistically non‐significant rate of change in OOD from 1999 to 2012 (APC = 0.47; P > 0.05), with a statistically significant and rapid acceleration in OOD rates in 2012 that persisted to 2018 (APC = 26.16; P 
doi_str_mv 10.1111/add.15233
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Methods Data were obtained from the CDC wide‐ranging on‐line data for epidemiological research, which combines OOD data from the National Vital Statistics System, and population data from the US Census Bureau. Joinpoint regression models were used to estimate age‐adjusted annual percentage change (APC) in OOD by race from 1999 to 2018. Results The temporal trends of OOD varied by race. African Americans had a persistently low rate of OOD and statistically non‐significant rate of change in OOD from 1999 to 2012 (APC = 0.47; P > 0.05), with a statistically significant and rapid acceleration in OOD rates in 2012 that persisted to 2018 (APC = 26.16; P < 0.01). Whites had three statistically significant periods of acceleration in OOD rate from 1999 to 2006 (APC = 12.43; P < 0.01), 2006 to 2013 (APC = 4.34, P < 0.01) and the greatest increase from 2013 to 2016 (APC = 18.96; P < 0.01). Whites had a statistically non‐significant decrease in OOD from 2016 to 2018 (P = 0.16). The trend for whites more closely aligned with the CDC‐defined epidemic periods than for African Americans. During wave 1 (1999–2010), the average annual percentage change (AAPC) for African Americans was significantly lower than for whites (0.47 versus 9.42, P < 0.01); however, by wave 3 (2013–current; defined by the introduction of illicitly manufactured fentanyl), the AAPC was significantly higher in African Americans (26.16 versus 13.19, P < 0.01). Conclusions Despite historically lower rates of opioid misuse and opioid‐involved overdose deaths among African Americans compared with whites, the growth in opioid‐involved overdose deaths among African Americans now outpaces that of whites in the United States.]]></description><identifier>ISSN: 0965-2140</identifier><identifier>EISSN: 1360-0443</identifier><identifier>DOI: 10.1111/add.15233</identifier><identifier>PMID: 32852864</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>African Americans ; Averages ; Censuses ; Drug addiction ; Drug overdose ; Epidemics ; Epidemiology ; Fentanyl ; health disparities ; health equity ; Narcotics ; opioid ; Opioids ; Overdose ; policy ; Race ; Racial differences ; Regression analysis ; Statistical analysis ; Trends ; White people</subject><ispartof>Addiction (Abingdon, England), 2021-03, Vol.116 (3), p.677-683</ispartof><rights>2020 Society for the Study of Addiction</rights><rights>2020 Society for the Study of Addiction.</rights><rights>2021 Society for the Study of Addiction</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3533-94a111d9ccce593063662cab5ffa91ed309fa009349e05a19ba4760afe870e033</citedby><cites>FETCH-LOGICAL-c3533-94a111d9ccce593063662cab5ffa91ed309fa009349e05a19ba4760afe870e033</cites><orcidid>0000-0002-9337-9886 ; 0000-0001-9306-1598 ; 0000-0003-2452-6691 ; 0000-0002-5130-8561</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fadd.15233$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fadd.15233$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32852864$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Furr‐Holden, Debra</creatorcontrib><creatorcontrib>Milam, Adam J.</creatorcontrib><creatorcontrib>Wang, Ling</creatorcontrib><creatorcontrib>Sadler, Richard</creatorcontrib><title>African Americans now outpace whites in opioid‐involved overdose deaths: a comparison of temporal trends from 1999 to 2018</title><title>Addiction (Abingdon, England)</title><addtitle>Addiction</addtitle><description><![CDATA[Aims To estimate racial differences in rates of opioid‐involved overdose deaths (OOD) between whites and African Americans in the United States from 1999 to 2018 to (1) identify racial variation in the temporal trends of OOD during the 20‐year period and (2) compare trends in OOD rates between whites and African Americans using the Centers for Disease Control and Prevention's (CDC) three defined OOD epidemic periods. Methods Data were obtained from the CDC wide‐ranging on‐line data for epidemiological research, which combines OOD data from the National Vital Statistics System, and population data from the US Census Bureau. Joinpoint regression models were used to estimate age‐adjusted annual percentage change (APC) in OOD by race from 1999 to 2018. Results The temporal trends of OOD varied by race. African Americans had a persistently low rate of OOD and statistically non‐significant rate of change in OOD from 1999 to 2012 (APC = 0.47; P > 0.05), with a statistically significant and rapid acceleration in OOD rates in 2012 that persisted to 2018 (APC = 26.16; P < 0.01). Whites had three statistically significant periods of acceleration in OOD rate from 1999 to 2006 (APC = 12.43; P < 0.01), 2006 to 2013 (APC = 4.34, P < 0.01) and the greatest increase from 2013 to 2016 (APC = 18.96; P < 0.01). Whites had a statistically non‐significant decrease in OOD from 2016 to 2018 (P = 0.16). The trend for whites more closely aligned with the CDC‐defined epidemic periods than for African Americans. During wave 1 (1999–2010), the average annual percentage change (AAPC) for African Americans was significantly lower than for whites (0.47 versus 9.42, P < 0.01); however, by wave 3 (2013–current; defined by the introduction of illicitly manufactured fentanyl), the AAPC was significantly higher in African Americans (26.16 versus 13.19, P < 0.01). Conclusions Despite historically lower rates of opioid misuse and opioid‐involved overdose deaths among African Americans compared with whites, the growth in opioid‐involved overdose deaths among African Americans now outpaces that of whites in the United States.]]></description><subject>African Americans</subject><subject>Averages</subject><subject>Censuses</subject><subject>Drug addiction</subject><subject>Drug overdose</subject><subject>Epidemics</subject><subject>Epidemiology</subject><subject>Fentanyl</subject><subject>health disparities</subject><subject>health equity</subject><subject>Narcotics</subject><subject>opioid</subject><subject>Opioids</subject><subject>Overdose</subject><subject>policy</subject><subject>Race</subject><subject>Racial differences</subject><subject>Regression analysis</subject><subject>Statistical analysis</subject><subject>Trends</subject><subject>White people</subject><issn>0965-2140</issn><issn>1360-0443</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp10c9u1DAQBnALgehSOPACyBIXOKQdx3YSc1u1_JMqcYFzNGuPVVdJHOxkV5U48Ag8I0-C6RYOSPgyPvz0aUYfY88FnInyztG5M6FrKR-wjZANVKCUfMg2YBpd1ULBCXuS8w0AtJ1Rj9mJrDtdd43asG9bn4LFiW9HuvtkPsUDj-syoyV-uA4LZR4mHucQg_v5_UeY9nHYk-NxT8nFTNwRLtf5DUdu4zhjCjkW7_lC4xwTDnxJNLnMfYojF8YYvkReg-ieskceh0zP7ucp-_Lu7eeLD9XVp_cfL7ZXlZVaysooLFc6Y60lbSQ0smlqizvtPRpBToLxCGCkMgQahdmhahtAT10LBFKeslfH3DnFryvlpR9DtjQMOFFcc18r2Xa6xIhCX_5Db-KaprJdUV3btBpaXdTro7Ip5pzI93MKI6bbXkD_u5K-VNLfVVLsi_vEdTeS-yv_dFDA-REcwkC3_0_qt5eXx8hfp9OVAQ</recordid><startdate>202103</startdate><enddate>202103</enddate><creator>Furr‐Holden, Debra</creator><creator>Milam, Adam J.</creator><creator>Wang, Ling</creator><creator>Sadler, Richard</creator><general>Blackwell Publishing Ltd</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7TK</scope><scope>8BJ</scope><scope>FQK</scope><scope>JBE</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-9337-9886</orcidid><orcidid>https://orcid.org/0000-0001-9306-1598</orcidid><orcidid>https://orcid.org/0000-0003-2452-6691</orcidid><orcidid>https://orcid.org/0000-0002-5130-8561</orcidid></search><sort><creationdate>202103</creationdate><title>African Americans now outpace whites in opioid‐involved overdose deaths: a comparison of temporal trends from 1999 to 2018</title><author>Furr‐Holden, Debra ; Milam, Adam J. ; Wang, Ling ; Sadler, Richard</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3533-94a111d9ccce593063662cab5ffa91ed309fa009349e05a19ba4760afe870e033</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>African Americans</topic><topic>Averages</topic><topic>Censuses</topic><topic>Drug addiction</topic><topic>Drug overdose</topic><topic>Epidemics</topic><topic>Epidemiology</topic><topic>Fentanyl</topic><topic>health disparities</topic><topic>health equity</topic><topic>Narcotics</topic><topic>opioid</topic><topic>Opioids</topic><topic>Overdose</topic><topic>policy</topic><topic>Race</topic><topic>Racial differences</topic><topic>Regression analysis</topic><topic>Statistical analysis</topic><topic>Trends</topic><topic>White people</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Furr‐Holden, Debra</creatorcontrib><creatorcontrib>Milam, Adam J.</creatorcontrib><creatorcontrib>Wang, Ling</creatorcontrib><creatorcontrib>Sadler, Richard</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>International Bibliography of the Social Sciences (IBSS)</collection><collection>International Bibliography of the Social Sciences</collection><collection>International Bibliography of the Social Sciences</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Addiction (Abingdon, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Furr‐Holden, Debra</au><au>Milam, Adam J.</au><au>Wang, Ling</au><au>Sadler, Richard</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>African Americans now outpace whites in opioid‐involved overdose deaths: a comparison of temporal trends from 1999 to 2018</atitle><jtitle>Addiction (Abingdon, England)</jtitle><addtitle>Addiction</addtitle><date>2021-03</date><risdate>2021</risdate><volume>116</volume><issue>3</issue><spage>677</spage><epage>683</epage><pages>677-683</pages><issn>0965-2140</issn><eissn>1360-0443</eissn><abstract><![CDATA[Aims To estimate racial differences in rates of opioid‐involved overdose deaths (OOD) between whites and African Americans in the United States from 1999 to 2018 to (1) identify racial variation in the temporal trends of OOD during the 20‐year period and (2) compare trends in OOD rates between whites and African Americans using the Centers for Disease Control and Prevention's (CDC) three defined OOD epidemic periods. Methods Data were obtained from the CDC wide‐ranging on‐line data for epidemiological research, which combines OOD data from the National Vital Statistics System, and population data from the US Census Bureau. Joinpoint regression models were used to estimate age‐adjusted annual percentage change (APC) in OOD by race from 1999 to 2018. Results The temporal trends of OOD varied by race. African Americans had a persistently low rate of OOD and statistically non‐significant rate of change in OOD from 1999 to 2012 (APC = 0.47; P > 0.05), with a statistically significant and rapid acceleration in OOD rates in 2012 that persisted to 2018 (APC = 26.16; P < 0.01). Whites had three statistically significant periods of acceleration in OOD rate from 1999 to 2006 (APC = 12.43; P < 0.01), 2006 to 2013 (APC = 4.34, P < 0.01) and the greatest increase from 2013 to 2016 (APC = 18.96; P < 0.01). Whites had a statistically non‐significant decrease in OOD from 2016 to 2018 (P = 0.16). The trend for whites more closely aligned with the CDC‐defined epidemic periods than for African Americans. During wave 1 (1999–2010), the average annual percentage change (AAPC) for African Americans was significantly lower than for whites (0.47 versus 9.42, P < 0.01); however, by wave 3 (2013–current; defined by the introduction of illicitly manufactured fentanyl), the AAPC was significantly higher in African Americans (26.16 versus 13.19, P < 0.01). Conclusions Despite historically lower rates of opioid misuse and opioid‐involved overdose deaths among African Americans compared with whites, the growth in opioid‐involved overdose deaths among African Americans now outpaces that of whites in the United States.]]></abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>32852864</pmid><doi>10.1111/add.15233</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-9337-9886</orcidid><orcidid>https://orcid.org/0000-0001-9306-1598</orcidid><orcidid>https://orcid.org/0000-0003-2452-6691</orcidid><orcidid>https://orcid.org/0000-0002-5130-8561</orcidid></addata></record>
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subjects African Americans
Averages
Censuses
Drug addiction
Drug overdose
Epidemics
Epidemiology
Fentanyl
health disparities
health equity
Narcotics
opioid
Opioids
Overdose
policy
Race
Racial differences
Regression analysis
Statistical analysis
Trends
White people
title African Americans now outpace whites in opioid‐involved overdose deaths: a comparison of temporal trends from 1999 to 2018
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