Critical illness-associated cerebral microbleed in a patient with sickle cell disease: A case report and review of the literature

Critical illness–associated cerebral microbleed (CICM) is a relatively rare and newly described condition. It can occur in critically ill ICU patients and can be secondary to many underlying etiologies. CICM is associated with high mortality and permanent neurologic deficits in surviving patients. Distribution of cerebral microhemorrhages in neuroimaging findings is critical for accurate diagnosis of this condition. Here, we present an ICU admitted patient with sickle cell disease crisis and CICM and will discuss their clinically and radiologically distinct phenomenon followed by a review of current literature. •CICM is a relatively rare and newly described form of cerebral microhemorrhage.•CICM can occur in sickle cell disease patients.•CICM mainly involves the gray-white matter junction of the brain.