Circular RNA has_circ_0000034 accelerates retinoblastoma advancement through the miR-361-3p/ADAM19 axis

Retinoblastoma (RB) is an intraocular malignancy that mainly occurs in infants and young children under 5 years of age. Circular RNA hsa_circ_0000034 (circ_0000034) was reported to be upregulated in RB tissues. Nevertheless, the function and mechanism of circ_0000034 in RB are unclear. Expression of...

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Veröffentlicht in:	Molecular and cellular biochemistry 2021, Vol.476 (1), p.69-80
Hauptverfasser:	Jiang, Yanhua, Xiao, Fan, Wang, Lin, Wang, Ting, Chen, Linlin
Format:	Artikel
Sprache:	eng
Schlagworte:	ADAM protein ADAM Proteins - genetics ADAM Proteins - metabolism Analysis Animal experimentation Apoptosis Assaying Biochemistry Biomedical and Life Sciences Cancer Cardiology Caspase-3 Cell Line, Tumor Cell migration Cell Movement Cell Proliferation Cell Survival Cell viability Child, Preschool Children Cholecystokinin Circular RNA Flow Cytometry Gene Expression Regulation, Neoplastic Gene Silencing Humans Immunoprecipitation Infant Infant, Newborn Infants Life Sciences Malignancy Medical Biochemistry MicroRNAs - genetics MicroRNAs - metabolism miRNA Neoplasm Invasiveness Oncology Polymerase chain reaction Retina Retinal Neoplasms - genetics Retinal Neoplasms - metabolism Retinoblastoma Retinoblastoma - genetics Retinoblastoma - metabolism Ribonucleic acid RNA RNA - metabolism RNA, Circular - genetics Tumors Up-Regulation
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