Regulatory T cell subsets in bullous pemphigoid and dipeptidyl peptidase-4 inhibitor-associated bullous pemphigoid

•Treg cells were increased in conventional BP patients before treatment.•Treg cells were not increased in dipeptidyl peptidase-4 inhibitor-associated BP.•Effector Treg cells positively correlated with disease severity in conventional BP. Regulatory T (Treg) cells play an essential role in peripheral...

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Veröffentlicht in:	Journal of dermatological science 2020-10, Vol.100 (1), p.23-30
Hauptverfasser:	Muramatsu, Ken, Zheng, Miao, Yoshimoto, Norihiro, Ito, Takamasa, Ujiie, Inkin, Iwata, Hiroaki, Shimizu, Hiroshi, Ujiie, Hideyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Autoantibodies - immunology Autoantibodies - metabolism Autoantigens - immunology Bullous pemphigoid Bullous pemphigoid disease area index Case-Control Studies CD4 Lymphocyte Count CD45RA Collagen Type XVII Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - drug therapy Dipeptidyl-Peptidase IV Inhibitors - adverse effects DPP-4 inhibitor Dystonin - immunology Female Glucocorticoids - administration & dosage Healthy Volunteers Humans Male Middle Aged Non-Fibrillar Collagens - immunology Pemphigoid, Bullous - blood Pemphigoid, Bullous - chemically induced Pemphigoid, Bullous - diagnosis Pemphigoid, Bullous - immunology Regulatory T cell subset Severity of Illness Index T-Lymphocyte Subsets - drug effects T-Lymphocyte Subsets - immunology T-Lymphocyte Subsets - metabolism T-Lymphocytes, Regulatory - drug effects T-Lymphocytes, Regulatory - immunology T-Lymphocytes, Regulatory - metabolism
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