Arterial Stiffness Is Associated with Clinical Outcome and Cardiorenal Injury in Lateralized Primary Aldosteronism
Abstract Context The association between arterial stiffness and clinical outcome in lateralized primary aldosteronism (PA) patients after adrenalectomy has not been clearly identified. Objective We hypothesized that arterial stiffness estimated by brachial-ankle pulse wave velocity (baPWV) before ad...
Gespeichert in:
| Veröffentlicht in: | The journal of clinical endocrinology and metabolism 2020-11, Vol.105 (11), p.1-e3960 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e3960 |
|---|---|
| container_issue | 11 |
| container_start_page | 1 |
| container_title | The journal of clinical endocrinology and metabolism |
| container_volume | 105 |
| creator | Chan, Chieh-Kai Yang, Wei-Shiung Lin, Yen-Hung Huang, Kuo-How Lu, Ching-Chu Hu, Ya-Hui Wu, Vin-Cent Chueh, Jeff S Chu, Tzong-Shinn Chen, Yung-Ming |
| description | Abstract
Context
The association between arterial stiffness and clinical outcome in lateralized primary aldosteronism (PA) patients after adrenalectomy has not been clearly identified.
Objective
We hypothesized that arterial stiffness estimated by brachial-ankle pulse wave velocity (baPWV) before adrenalectomy was associated with the clinical outcomes and cardiorenal injury in lateralized PA patients after adrenalectomy.
Design and Patients
We designed a retrospective observational cohort study. We collected lateralized PA patients who had undergone adrenalectomy between 2013 and 2016 from the Taiwan Primary Aldosteronism Investigation database. The primary outcome was achieving complete clinical success at 1 year after adrenalectomy. The secondary outcome was estimated glomerular filtration rate declining over 20% and improved left ventricular mass index.
Results
We enrolled 221 patients with lateralized PA (50.7% men; mean age, 51.9 years), of whom 101 patients (45.7%) achieved complete clinical success at the 1-year follow-up assessment after adrenalectomy. Lower baPWV before adrenalectomy (odds ratio = 0.998; 95% confidence interval, 0.996-0.999; P = 0.003) correlated with higher likelihood of complete clinical success by multivariate logistic regression analysis. Multifactorial adjusted generalized additive model demonstrated that preoperative baPWV |
| doi_str_mv | 10.1210/clinem/dgaa566 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_2437121085</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A702048137</galeid><oup_id>10.1210/clinem/dgaa566</oup_id><sourcerecordid>A702048137</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5076-7ce8f50d6c7401c06eecf623572135268e95e76bc61cd38e92f7b2bcb07221493</originalsourceid><addsrcrecordid>eNqFkc-L1DAUx4Mo7rh69SgFL3robn40SXssg6sDAyuo4C2k6etOxjQZk5ZB__rN0FFBViSHkC-f73vfvIfQS4KvCCX42jjrYbzu77TmQjxCK9JUvJSkkY_RCmNKykbSrxfoWUp7jElVcfYUXTBaM864XKHYxgmi1a74NNlh8JBSsUlFm1IwVk_QF0c77Yp1bmNNpm7nyYQRCu37Yq1jb0MEn_WN38_xR2F9sc2uqJ39mb0fox11llvXh5Tl4G0an6Mng3YJXpzvS_Tl5t3n9Ydye_t-s263peFYilIaqAeOe2FkhYnBAsAMgubUlDBORQ0NByk6I4jpWX7RQXa0Mx2WlJKqYZfozVL3EMP3GdKkRpsMOKc9hDkpWjF5mmHNM_r6L3Qf5pj_daIkwQznxn-oO-1AWT-EKWpzKqpaiSmuasJkpq4eoPLpYbQmeBhs1h8ymBhSijCowzI2RbA6BVTLktV5ydnw6px27kbof-O_tpoBugDH4PLU0zc3HyGqHWg37f5d9e1iCvPhfwnuARPhwyw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2471030623</pqid></control><display><type>article</type><title>Arterial Stiffness Is Associated with Clinical Outcome and Cardiorenal Injury in Lateralized Primary Aldosteronism</title><source>ProQuest One Community College</source><source>MEDLINE</source><source>ProQuest Central (Alumni Edition)</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Oxford University Press Journals All Titles (1996-Current)</source><source>ProQuest Central UK/Ireland</source><source>Alma/SFX Local Collection</source><source>ProQuest Central</source><creator>Chan, Chieh-Kai ; Yang, Wei-Shiung ; Lin, Yen-Hung ; Huang, Kuo-How ; Lu, Ching-Chu ; Hu, Ya-Hui ; Wu, Vin-Cent ; Chueh, Jeff S ; Chu, Tzong-Shinn ; Chen, Yung-Ming</creator><creatorcontrib>Chan, Chieh-Kai ; Yang, Wei-Shiung ; Lin, Yen-Hung ; Huang, Kuo-How ; Lu, Ching-Chu ; Hu, Ya-Hui ; Wu, Vin-Cent ; Chueh, Jeff S ; Chu, Tzong-Shinn ; Chen, Yung-Ming</creatorcontrib><description>Abstract
Context
The association between arterial stiffness and clinical outcome in lateralized primary aldosteronism (PA) patients after adrenalectomy has not been clearly identified.
Objective
We hypothesized that arterial stiffness estimated by brachial-ankle pulse wave velocity (baPWV) before adrenalectomy was associated with the clinical outcomes and cardiorenal injury in lateralized PA patients after adrenalectomy.
Design and Patients
We designed a retrospective observational cohort study. We collected lateralized PA patients who had undergone adrenalectomy between 2013 and 2016 from the Taiwan Primary Aldosteronism Investigation database. The primary outcome was achieving complete clinical success at 1 year after adrenalectomy. The secondary outcome was estimated glomerular filtration rate declining over 20% and improved left ventricular mass index.
Results
We enrolled 221 patients with lateralized PA (50.7% men; mean age, 51.9 years), of whom 101 patients (45.7%) achieved complete clinical success at the 1-year follow-up assessment after adrenalectomy. Lower baPWV before adrenalectomy (odds ratio = 0.998; 95% confidence interval, 0.996-0.999; P = 0.003) correlated with higher likelihood of complete clinical success by multivariate logistic regression analysis. Multifactorial adjusted generalized additive model demonstrated that preoperative baPWV<1600 cm/sec was significantly associated with complete cure of hypertension. In addition, higher preoperative baPWV was associated with renal function decline and less left ventricular mass regression after adrenalectomy in lateralized PA patients during the follow-up period.
Conclusions
Our study demonstrated that the preoperative severe arterial stiffness was associated with absent complete clinical success in lateralized PA patients after adrenalectomy, and this effect may contribute to cardiorenal injury, which at least partially explains kidney function deterioration and lessened regression of heart mass.</description><identifier>ISSN: 0021-972X</identifier><identifier>EISSN: 1945-7197</identifier><identifier>DOI: 10.1210/clinem/dgaa566</identifier><identifier>PMID: 32835357</identifier><language>eng</language><publisher>US: Oxford University Press</publisher><subject>Adrenalectomy ; Adult ; Aged ; Ankle ; Ankle Brachial Index ; Brachial Artery - diagnostic imaging ; Brachial Artery - physiopathology ; Echocardiography ; Endocrine disorders ; Female ; Glomerular filtration rate ; Glomerular Filtration Rate - physiology ; Heart ; Humans ; Hyperaldosteronism ; Hyperaldosteronism - diagnostic imaging ; Hyperaldosteronism - physiopathology ; Hyperaldosteronism - surgery ; Hypertension ; Male ; Medical research ; Medicine, Experimental ; Middle Aged ; Patient outcomes ; Pulse Wave Analysis ; Renal function ; Retrospective Studies ; Success ; Treatment Outcome ; Vascular Stiffness - physiology ; Ventricle</subject><ispartof>The journal of clinical endocrinology and metabolism, 2020-11, Vol.105 (11), p.1-e3960</ispartof><rights>Endocrine Society 2020. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com 2020</rights><rights>Copyright © Oxford University Press 2015</rights><rights>Endocrine Society 2020. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.</rights><rights>COPYRIGHT 2020 Oxford University Press</rights><rights>Endocrine Society 2020. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5076-7ce8f50d6c7401c06eecf623572135268e95e76bc61cd38e92f7b2bcb07221493</citedby><cites>FETCH-LOGICAL-c5076-7ce8f50d6c7401c06eecf623572135268e95e76bc61cd38e92f7b2bcb07221493</cites><orcidid>0000-0001-8153-1441 ; 0000-0003-4529-3161 ; 0000-0001-7935-0991</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/2471030623?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,777,781,21369,21370,27905,27906,33511,33512,33725,33726,43640,43786,64364,64366,64368,72218,72872,72877,72878,72880</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32835357$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chan, Chieh-Kai</creatorcontrib><creatorcontrib>Yang, Wei-Shiung</creatorcontrib><creatorcontrib>Lin, Yen-Hung</creatorcontrib><creatorcontrib>Huang, Kuo-How</creatorcontrib><creatorcontrib>Lu, Ching-Chu</creatorcontrib><creatorcontrib>Hu, Ya-Hui</creatorcontrib><creatorcontrib>Wu, Vin-Cent</creatorcontrib><creatorcontrib>Chueh, Jeff S</creatorcontrib><creatorcontrib>Chu, Tzong-Shinn</creatorcontrib><creatorcontrib>Chen, Yung-Ming</creatorcontrib><title>Arterial Stiffness Is Associated with Clinical Outcome and Cardiorenal Injury in Lateralized Primary Aldosteronism</title><title>The journal of clinical endocrinology and metabolism</title><addtitle>J Clin Endocrinol Metab</addtitle><description>Abstract
Context
The association between arterial stiffness and clinical outcome in lateralized primary aldosteronism (PA) patients after adrenalectomy has not been clearly identified.
Objective
We hypothesized that arterial stiffness estimated by brachial-ankle pulse wave velocity (baPWV) before adrenalectomy was associated with the clinical outcomes and cardiorenal injury in lateralized PA patients after adrenalectomy.
Design and Patients
We designed a retrospective observational cohort study. We collected lateralized PA patients who had undergone adrenalectomy between 2013 and 2016 from the Taiwan Primary Aldosteronism Investigation database. The primary outcome was achieving complete clinical success at 1 year after adrenalectomy. The secondary outcome was estimated glomerular filtration rate declining over 20% and improved left ventricular mass index.
Results
We enrolled 221 patients with lateralized PA (50.7% men; mean age, 51.9 years), of whom 101 patients (45.7%) achieved complete clinical success at the 1-year follow-up assessment after adrenalectomy. Lower baPWV before adrenalectomy (odds ratio = 0.998; 95% confidence interval, 0.996-0.999; P = 0.003) correlated with higher likelihood of complete clinical success by multivariate logistic regression analysis. Multifactorial adjusted generalized additive model demonstrated that preoperative baPWV<1600 cm/sec was significantly associated with complete cure of hypertension. In addition, higher preoperative baPWV was associated with renal function decline and less left ventricular mass regression after adrenalectomy in lateralized PA patients during the follow-up period.
Conclusions
Our study demonstrated that the preoperative severe arterial stiffness was associated with absent complete clinical success in lateralized PA patients after adrenalectomy, and this effect may contribute to cardiorenal injury, which at least partially explains kidney function deterioration and lessened regression of heart mass.</description><subject>Adrenalectomy</subject><subject>Adult</subject><subject>Aged</subject><subject>Ankle</subject><subject>Ankle Brachial Index</subject><subject>Brachial Artery - diagnostic imaging</subject><subject>Brachial Artery - physiopathology</subject><subject>Echocardiography</subject><subject>Endocrine disorders</subject><subject>Female</subject><subject>Glomerular filtration rate</subject><subject>Glomerular Filtration Rate - physiology</subject><subject>Heart</subject><subject>Humans</subject><subject>Hyperaldosteronism</subject><subject>Hyperaldosteronism - diagnostic imaging</subject><subject>Hyperaldosteronism - physiopathology</subject><subject>Hyperaldosteronism - surgery</subject><subject>Hypertension</subject><subject>Male</subject><subject>Medical research</subject><subject>Medicine, Experimental</subject><subject>Middle Aged</subject><subject>Patient outcomes</subject><subject>Pulse Wave Analysis</subject><subject>Renal function</subject><subject>Retrospective Studies</subject><subject>Success</subject><subject>Treatment Outcome</subject><subject>Vascular Stiffness - physiology</subject><subject>Ventricle</subject><issn>0021-972X</issn><issn>1945-7197</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqFkc-L1DAUx4Mo7rh69SgFL3robn40SXssg6sDAyuo4C2k6etOxjQZk5ZB__rN0FFBViSHkC-f73vfvIfQS4KvCCX42jjrYbzu77TmQjxCK9JUvJSkkY_RCmNKykbSrxfoWUp7jElVcfYUXTBaM864XKHYxgmi1a74NNlh8JBSsUlFm1IwVk_QF0c77Yp1bmNNpm7nyYQRCu37Yq1jb0MEn_WN38_xR2F9sc2uqJ39mb0fox11llvXh5Tl4G0an6Mng3YJXpzvS_Tl5t3n9Ydye_t-s263peFYilIaqAeOe2FkhYnBAsAMgubUlDBORQ0NByk6I4jpWX7RQXa0Mx2WlJKqYZfozVL3EMP3GdKkRpsMOKc9hDkpWjF5mmHNM_r6L3Qf5pj_daIkwQznxn-oO-1AWT-EKWpzKqpaiSmuasJkpq4eoPLpYbQmeBhs1h8ymBhSijCowzI2RbA6BVTLktV5ydnw6px27kbof-O_tpoBugDH4PLU0zc3HyGqHWg37f5d9e1iCvPhfwnuARPhwyw</recordid><startdate>20201101</startdate><enddate>20201101</enddate><creator>Chan, Chieh-Kai</creator><creator>Yang, Wei-Shiung</creator><creator>Lin, Yen-Hung</creator><creator>Huang, Kuo-How</creator><creator>Lu, Ching-Chu</creator><creator>Hu, Ya-Hui</creator><creator>Wu, Vin-Cent</creator><creator>Chueh, Jeff S</creator><creator>Chu, Tzong-Shinn</creator><creator>Chen, Yung-Ming</creator><general>Oxford University Press</general><general>Copyright Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7T5</scope><scope>7TM</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-8153-1441</orcidid><orcidid>https://orcid.org/0000-0003-4529-3161</orcidid><orcidid>https://orcid.org/0000-0001-7935-0991</orcidid></search><sort><creationdate>20201101</creationdate><title>Arterial Stiffness Is Associated with Clinical Outcome and Cardiorenal Injury in Lateralized Primary Aldosteronism</title><author>Chan, Chieh-Kai ; Yang, Wei-Shiung ; Lin, Yen-Hung ; Huang, Kuo-How ; Lu, Ching-Chu ; Hu, Ya-Hui ; Wu, Vin-Cent ; Chueh, Jeff S ; Chu, Tzong-Shinn ; Chen, Yung-Ming</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5076-7ce8f50d6c7401c06eecf623572135268e95e76bc61cd38e92f7b2bcb07221493</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adrenalectomy</topic><topic>Adult</topic><topic>Aged</topic><topic>Ankle</topic><topic>Ankle Brachial Index</topic><topic>Brachial Artery - diagnostic imaging</topic><topic>Brachial Artery - physiopathology</topic><topic>Echocardiography</topic><topic>Endocrine disorders</topic><topic>Female</topic><topic>Glomerular filtration rate</topic><topic>Glomerular Filtration Rate - physiology</topic><topic>Heart</topic><topic>Humans</topic><topic>Hyperaldosteronism</topic><topic>Hyperaldosteronism - diagnostic imaging</topic><topic>Hyperaldosteronism - physiopathology</topic><topic>Hyperaldosteronism - surgery</topic><topic>Hypertension</topic><topic>Male</topic><topic>Medical research</topic><topic>Medicine, Experimental</topic><topic>Middle Aged</topic><topic>Patient outcomes</topic><topic>Pulse Wave Analysis</topic><topic>Renal function</topic><topic>Retrospective Studies</topic><topic>Success</topic><topic>Treatment Outcome</topic><topic>Vascular Stiffness - physiology</topic><topic>Ventricle</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chan, Chieh-Kai</creatorcontrib><creatorcontrib>Yang, Wei-Shiung</creatorcontrib><creatorcontrib>Lin, Yen-Hung</creatorcontrib><creatorcontrib>Huang, Kuo-How</creatorcontrib><creatorcontrib>Lu, Ching-Chu</creatorcontrib><creatorcontrib>Hu, Ya-Hui</creatorcontrib><creatorcontrib>Wu, Vin-Cent</creatorcontrib><creatorcontrib>Chueh, Jeff S</creatorcontrib><creatorcontrib>Chu, Tzong-Shinn</creatorcontrib><creatorcontrib>Chen, Yung-Ming</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Immunology Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>The journal of clinical endocrinology and metabolism</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chan, Chieh-Kai</au><au>Yang, Wei-Shiung</au><au>Lin, Yen-Hung</au><au>Huang, Kuo-How</au><au>Lu, Ching-Chu</au><au>Hu, Ya-Hui</au><au>Wu, Vin-Cent</au><au>Chueh, Jeff S</au><au>Chu, Tzong-Shinn</au><au>Chen, Yung-Ming</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Arterial Stiffness Is Associated with Clinical Outcome and Cardiorenal Injury in Lateralized Primary Aldosteronism</atitle><jtitle>The journal of clinical endocrinology and metabolism</jtitle><addtitle>J Clin Endocrinol Metab</addtitle><date>2020-11-01</date><risdate>2020</risdate><volume>105</volume><issue>11</issue><spage>1</spage><epage>e3960</epage><pages>1-e3960</pages><issn>0021-972X</issn><eissn>1945-7197</eissn><abstract>Abstract
Context
The association between arterial stiffness and clinical outcome in lateralized primary aldosteronism (PA) patients after adrenalectomy has not been clearly identified.
Objective
We hypothesized that arterial stiffness estimated by brachial-ankle pulse wave velocity (baPWV) before adrenalectomy was associated with the clinical outcomes and cardiorenal injury in lateralized PA patients after adrenalectomy.
Design and Patients
We designed a retrospective observational cohort study. We collected lateralized PA patients who had undergone adrenalectomy between 2013 and 2016 from the Taiwan Primary Aldosteronism Investigation database. The primary outcome was achieving complete clinical success at 1 year after adrenalectomy. The secondary outcome was estimated glomerular filtration rate declining over 20% and improved left ventricular mass index.
Results
We enrolled 221 patients with lateralized PA (50.7% men; mean age, 51.9 years), of whom 101 patients (45.7%) achieved complete clinical success at the 1-year follow-up assessment after adrenalectomy. Lower baPWV before adrenalectomy (odds ratio = 0.998; 95% confidence interval, 0.996-0.999; P = 0.003) correlated with higher likelihood of complete clinical success by multivariate logistic regression analysis. Multifactorial adjusted generalized additive model demonstrated that preoperative baPWV<1600 cm/sec was significantly associated with complete cure of hypertension. In addition, higher preoperative baPWV was associated with renal function decline and less left ventricular mass regression after adrenalectomy in lateralized PA patients during the follow-up period.
Conclusions
Our study demonstrated that the preoperative severe arterial stiffness was associated with absent complete clinical success in lateralized PA patients after adrenalectomy, and this effect may contribute to cardiorenal injury, which at least partially explains kidney function deterioration and lessened regression of heart mass.</abstract><cop>US</cop><pub>Oxford University Press</pub><pmid>32835357</pmid><doi>10.1210/clinem/dgaa566</doi><orcidid>https://orcid.org/0000-0001-8153-1441</orcidid><orcidid>https://orcid.org/0000-0003-4529-3161</orcidid><orcidid>https://orcid.org/0000-0001-7935-0991</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0021-972X |
| ispartof | The journal of clinical endocrinology and metabolism, 2020-11, Vol.105 (11), p.1-e3960 |
| issn | 0021-972X 1945-7197 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2437121085 |
| source | ProQuest One Community College; MEDLINE; ProQuest Central (Alumni Edition); Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Oxford University Press Journals All Titles (1996-Current); ProQuest Central UK/Ireland; Alma/SFX Local Collection; ProQuest Central |
| subjects | Adrenalectomy Adult Aged Ankle Ankle Brachial Index Brachial Artery - diagnostic imaging Brachial Artery - physiopathology Echocardiography Endocrine disorders Female Glomerular filtration rate Glomerular Filtration Rate - physiology Heart Humans Hyperaldosteronism Hyperaldosteronism - diagnostic imaging Hyperaldosteronism - physiopathology Hyperaldosteronism - surgery Hypertension Male Medical research Medicine, Experimental Middle Aged Patient outcomes Pulse Wave Analysis Renal function Retrospective Studies Success Treatment Outcome Vascular Stiffness - physiology Ventricle |
| title | Arterial Stiffness Is Associated with Clinical Outcome and Cardiorenal Injury in Lateralized Primary Aldosteronism |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-18T18%3A54%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Arterial%20Stiffness%20Is%20Associated%20with%20Clinical%20Outcome%20and%20Cardiorenal%20Injury%20in%20Lateralized%20Primary%20Aldosteronism&rft.jtitle=The%20journal%20of%20clinical%20endocrinology%20and%20metabolism&rft.au=Chan,%20Chieh-Kai&rft.date=2020-11-01&rft.volume=105&rft.issue=11&rft.spage=1&rft.epage=e3960&rft.pages=1-e3960&rft.issn=0021-972X&rft.eissn=1945-7197&rft_id=info:doi/10.1210/clinem/dgaa566&rft_dat=%3Cgale_proqu%3EA702048137%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2471030623&rft_id=info:pmid/32835357&rft_galeid=A702048137&rft_oup_id=10.1210/clinem/dgaa566&rfr_iscdi=true |