Quantitative assessment of terminal ileum motility on MR enterography in Crohn disease: a feasibility study in children
Objectives Investigate the relationship between quantified terminal ileal (TI) motility and histopathological activity grading, Crohn Disease MRI Index (CDMI) and faecal calprotectin. Methods Retrospective review of children with Crohn disease or unclassified inflammatory bowel disease, who underwen...
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| Veröffentlicht in: | European radiology 2021-02, Vol.31 (2), p.775-784 |
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| creator | Cococcioni, Lucia Fitzke, Heather Menys, Alex Gaunt, Trevor Kumar, Shankar Kiparissi, Fevronia Rampling, Dyanne Palm, Liina Taylor, Stuart A. Watson, Tom A. |
| description | Objectives
Investigate the relationship between quantified terminal ileal (TI) motility and histopathological activity grading, Crohn Disease MRI Index (CDMI) and faecal calprotectin.
Methods
Retrospective review of children with Crohn disease or unclassified inflammatory bowel disease, who underwent MR enterography. Dynamic imaging for 25 patients (median age 12, range 5 to 16) was analysed with a validated motility algorithm. The TI motility score was derived. The primary reference standard was TI Endoscopic biopsy Assessment of Inflammatory Activity (eAIS) within 40 days of the MR enterography. Secondary reference standards: (1) the Crohn Disease MRI Index (CDMI) and (2) faecal calprotectin levels.
Results
MR enterography median motility score was 0.17 a.u. (IQR 0.12 to 0.25; range 0.05 to 0.55), and median CDMI was 3 (IQR 0 to 5.5). Forty-three percent of patients had active disease (eAIS > 0) with a median eAIS score of 0 (IQR 0 to 2; range 0 to 5). The correlation between eAIS and motility was
r
= − 0.58 (
p
= 0.004,
N
= 23). Between CDMI and motility,
r
= − 0.42 (
p
= 0.037,
N
= 25). Motility score was lower in active disease (median 0.12 vs 0.21,
p
= 0.020) while CDMI was higher (median 5 vs 1,
p
= 0.04). In a subset of 12 patients with faecal calprotectin within 3 months of MR enterography, correlation with motility was
r
= − 0.27 (
p
= 0.4).
Conclusions
Quantified terminal ileum motility decreases with increasing histopathological abnormality in children with Crohn disease, reproducing findings in adults. TI motility showed a negative correlation with an MRI activity score but not with faecal calprotectin levels.
Key Points
• It is feasible to perform MRI quantified bowel motility assessment in children using free-breathing techniques.
• Bowel motility in children with Crohn disease decreases as the extent of intestinal inflammation increases.
• Quantified intestinal motility may be a candidate biomarker for treatment efficacy in children with Crohn disease. |
| doi_str_mv | 10.1007/s00330-020-07084-1 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2436873403</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2436873403</sourcerecordid><originalsourceid>FETCH-LOGICAL-c419t-139ff12caf686c71f7ec0fed2e70a6c3c66c26dba8d7ac37e0aa3c185b29b87c3</originalsourceid><addsrcrecordid>eNp9kU9PFTEUxRuDkcfTL-DCNGHDZqR_xrbDzrygmECMBNdNp3PLK5lpH21H8r69hUFNXLC46W36O-em9yD0npKPlBB5mgnhnDSE1ZJEtQ19hVa05ayh9XaAVqTjqpFd1x6io5zvCCEdbeUbdMiZqsqOrNDDj9mE4osp_hdgkzPkPEEoODpcIE0-mBH7EeYJT7H40Zc9jgFfXeMKQYq3yey2e-wD3qS4DXjwGUyGM2ywq43vF0ku8_BE2a0fhwThLXrtzJjh3fO5Rj-_nN9sLprL71-_bT5fNralXWko75yjzBonlLCSOgmWOBgYSGKE5VYIy8TQGzVIY7kEYgy3VH3qWdcrafkanSy-uxTvZ8hFTz5bGEcTIM5Zs5YLJXlbN7lGx_-hd3FO9f-PlFRC1EW2lWILZVPMOYHTu-Qnk_aaEv0Yi15i0TUW_RSLplX04dl67icY_kr-5FABvgC5PoVbSP9mv2D7Gyzpmik</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2478669944</pqid></control><display><type>article</type><title>Quantitative assessment of terminal ileum motility on MR enterography in Crohn disease: a feasibility study in children</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Cococcioni, Lucia ; Fitzke, Heather ; Menys, Alex ; Gaunt, Trevor ; Kumar, Shankar ; Kiparissi, Fevronia ; Rampling, Dyanne ; Palm, Liina ; Taylor, Stuart A. ; Watson, Tom A.</creator><creatorcontrib>Cococcioni, Lucia ; Fitzke, Heather ; Menys, Alex ; Gaunt, Trevor ; Kumar, Shankar ; Kiparissi, Fevronia ; Rampling, Dyanne ; Palm, Liina ; Taylor, Stuart A. ; Watson, Tom A.</creatorcontrib><description>Objectives
Investigate the relationship between quantified terminal ileal (TI) motility and histopathological activity grading, Crohn Disease MRI Index (CDMI) and faecal calprotectin.
Methods
Retrospective review of children with Crohn disease or unclassified inflammatory bowel disease, who underwent MR enterography. Dynamic imaging for 25 patients (median age 12, range 5 to 16) was analysed with a validated motility algorithm. The TI motility score was derived. The primary reference standard was TI Endoscopic biopsy Assessment of Inflammatory Activity (eAIS) within 40 days of the MR enterography. Secondary reference standards: (1) the Crohn Disease MRI Index (CDMI) and (2) faecal calprotectin levels.
Results
MR enterography median motility score was 0.17 a.u. (IQR 0.12 to 0.25; range 0.05 to 0.55), and median CDMI was 3 (IQR 0 to 5.5). Forty-three percent of patients had active disease (eAIS > 0) with a median eAIS score of 0 (IQR 0 to 2; range 0 to 5). The correlation between eAIS and motility was
r
= − 0.58 (
p
= 0.004,
N
= 23). Between CDMI and motility,
r
= − 0.42 (
p
= 0.037,
N
= 25). Motility score was lower in active disease (median 0.12 vs 0.21,
p
= 0.020) while CDMI was higher (median 5 vs 1,
p
= 0.04). In a subset of 12 patients with faecal calprotectin within 3 months of MR enterography, correlation with motility was
r
= − 0.27 (
p
= 0.4).
Conclusions
Quantified terminal ileum motility decreases with increasing histopathological abnormality in children with Crohn disease, reproducing findings in adults. TI motility showed a negative correlation with an MRI activity score but not with faecal calprotectin levels.
Key Points
• It is feasible to perform MRI quantified bowel motility assessment in children using free-breathing techniques.
• Bowel motility in children with Crohn disease decreases as the extent of intestinal inflammation increases.
• Quantified intestinal motility may be a candidate biomarker for treatment efficacy in children with Crohn disease.</description><identifier>ISSN: 0938-7994</identifier><identifier>EISSN: 1432-1084</identifier><identifier>DOI: 10.1007/s00330-020-07084-1</identifier><identifier>PMID: 32833090</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adult ; Algorithms ; Biomarkers ; Biopsy ; Child ; Children ; Crohn Disease - diagnostic imaging ; Diagnostic Radiology ; Feasibility Studies ; Humans ; Ileum ; Ileum - diagnostic imaging ; Imaging ; Inflammatory bowel diseases ; Internal Medicine ; Interventional Radiology ; Intestinal motility ; Intestine ; Magnetic Resonance Imaging ; Medical treatment ; Medicine ; Medicine & Public Health ; Motility ; Neuroradiology ; Paediatric ; Radiology ; Retrospective Studies ; Ultrasound</subject><ispartof>European radiology, 2021-02, Vol.31 (2), p.775-784</ispartof><rights>European Society of Radiology 2020</rights><rights>European Society of Radiology 2020.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c419t-139ff12caf686c71f7ec0fed2e70a6c3c66c26dba8d7ac37e0aa3c185b29b87c3</citedby><cites>FETCH-LOGICAL-c419t-139ff12caf686c71f7ec0fed2e70a6c3c66c26dba8d7ac37e0aa3c185b29b87c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00330-020-07084-1$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00330-020-07084-1$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32833090$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cococcioni, Lucia</creatorcontrib><creatorcontrib>Fitzke, Heather</creatorcontrib><creatorcontrib>Menys, Alex</creatorcontrib><creatorcontrib>Gaunt, Trevor</creatorcontrib><creatorcontrib>Kumar, Shankar</creatorcontrib><creatorcontrib>Kiparissi, Fevronia</creatorcontrib><creatorcontrib>Rampling, Dyanne</creatorcontrib><creatorcontrib>Palm, Liina</creatorcontrib><creatorcontrib>Taylor, Stuart A.</creatorcontrib><creatorcontrib>Watson, Tom A.</creatorcontrib><title>Quantitative assessment of terminal ileum motility on MR enterography in Crohn disease: a feasibility study in children</title><title>European radiology</title><addtitle>Eur Radiol</addtitle><addtitle>Eur Radiol</addtitle><description>Objectives
Investigate the relationship between quantified terminal ileal (TI) motility and histopathological activity grading, Crohn Disease MRI Index (CDMI) and faecal calprotectin.
Methods
Retrospective review of children with Crohn disease or unclassified inflammatory bowel disease, who underwent MR enterography. Dynamic imaging for 25 patients (median age 12, range 5 to 16) was analysed with a validated motility algorithm. The TI motility score was derived. The primary reference standard was TI Endoscopic biopsy Assessment of Inflammatory Activity (eAIS) within 40 days of the MR enterography. Secondary reference standards: (1) the Crohn Disease MRI Index (CDMI) and (2) faecal calprotectin levels.
Results
MR enterography median motility score was 0.17 a.u. (IQR 0.12 to 0.25; range 0.05 to 0.55), and median CDMI was 3 (IQR 0 to 5.5). Forty-three percent of patients had active disease (eAIS > 0) with a median eAIS score of 0 (IQR 0 to 2; range 0 to 5). The correlation between eAIS and motility was
r
= − 0.58 (
p
= 0.004,
N
= 23). Between CDMI and motility,
r
= − 0.42 (
p
= 0.037,
N
= 25). Motility score was lower in active disease (median 0.12 vs 0.21,
p
= 0.020) while CDMI was higher (median 5 vs 1,
p
= 0.04). In a subset of 12 patients with faecal calprotectin within 3 months of MR enterography, correlation with motility was
r
= − 0.27 (
p
= 0.4).
Conclusions
Quantified terminal ileum motility decreases with increasing histopathological abnormality in children with Crohn disease, reproducing findings in adults. TI motility showed a negative correlation with an MRI activity score but not with faecal calprotectin levels.
Key Points
• It is feasible to perform MRI quantified bowel motility assessment in children using free-breathing techniques.
• Bowel motility in children with Crohn disease decreases as the extent of intestinal inflammation increases.
• Quantified intestinal motility may be a candidate biomarker for treatment efficacy in children with Crohn disease.</description><subject>Adult</subject><subject>Algorithms</subject><subject>Biomarkers</subject><subject>Biopsy</subject><subject>Child</subject><subject>Children</subject><subject>Crohn Disease - diagnostic imaging</subject><subject>Diagnostic Radiology</subject><subject>Feasibility Studies</subject><subject>Humans</subject><subject>Ileum</subject><subject>Ileum - diagnostic imaging</subject><subject>Imaging</subject><subject>Inflammatory bowel diseases</subject><subject>Internal Medicine</subject><subject>Interventional Radiology</subject><subject>Intestinal motility</subject><subject>Intestine</subject><subject>Magnetic Resonance Imaging</subject><subject>Medical treatment</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Motility</subject><subject>Neuroradiology</subject><subject>Paediatric</subject><subject>Radiology</subject><subject>Retrospective Studies</subject><subject>Ultrasound</subject><issn>0938-7994</issn><issn>1432-1084</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kU9PFTEUxRuDkcfTL-DCNGHDZqR_xrbDzrygmECMBNdNp3PLK5lpH21H8r69hUFNXLC46W36O-em9yD0npKPlBB5mgnhnDSE1ZJEtQ19hVa05ayh9XaAVqTjqpFd1x6io5zvCCEdbeUbdMiZqsqOrNDDj9mE4osp_hdgkzPkPEEoODpcIE0-mBH7EeYJT7H40Zc9jgFfXeMKQYq3yey2e-wD3qS4DXjwGUyGM2ywq43vF0ku8_BE2a0fhwThLXrtzJjh3fO5Rj-_nN9sLprL71-_bT5fNralXWko75yjzBonlLCSOgmWOBgYSGKE5VYIy8TQGzVIY7kEYgy3VH3qWdcrafkanSy-uxTvZ8hFTz5bGEcTIM5Zs5YLJXlbN7lGx_-hd3FO9f-PlFRC1EW2lWILZVPMOYHTu-Qnk_aaEv0Yi15i0TUW_RSLplX04dl67icY_kr-5FABvgC5PoVbSP9mv2D7Gyzpmik</recordid><startdate>20210201</startdate><enddate>20210201</enddate><creator>Cococcioni, Lucia</creator><creator>Fitzke, Heather</creator><creator>Menys, Alex</creator><creator>Gaunt, Trevor</creator><creator>Kumar, Shankar</creator><creator>Kiparissi, Fevronia</creator><creator>Rampling, Dyanne</creator><creator>Palm, Liina</creator><creator>Taylor, Stuart A.</creator><creator>Watson, Tom A.</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>20210201</creationdate><title>Quantitative assessment of terminal ileum motility on MR enterography in Crohn disease: a feasibility study in children</title><author>Cococcioni, Lucia ; Fitzke, Heather ; Menys, Alex ; Gaunt, Trevor ; Kumar, Shankar ; Kiparissi, Fevronia ; Rampling, Dyanne ; Palm, Liina ; Taylor, Stuart A. ; Watson, Tom A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c419t-139ff12caf686c71f7ec0fed2e70a6c3c66c26dba8d7ac37e0aa3c185b29b87c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Adult</topic><topic>Algorithms</topic><topic>Biomarkers</topic><topic>Biopsy</topic><topic>Child</topic><topic>Children</topic><topic>Crohn Disease - diagnostic imaging</topic><topic>Diagnostic Radiology</topic><topic>Feasibility Studies</topic><topic>Humans</topic><topic>Ileum</topic><topic>Ileum - diagnostic imaging</topic><topic>Imaging</topic><topic>Inflammatory bowel diseases</topic><topic>Internal Medicine</topic><topic>Interventional Radiology</topic><topic>Intestinal motility</topic><topic>Intestine</topic><topic>Magnetic Resonance Imaging</topic><topic>Medical treatment</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Motility</topic><topic>Neuroradiology</topic><topic>Paediatric</topic><topic>Radiology</topic><topic>Retrospective Studies</topic><topic>Ultrasound</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cococcioni, Lucia</creatorcontrib><creatorcontrib>Fitzke, Heather</creatorcontrib><creatorcontrib>Menys, Alex</creatorcontrib><creatorcontrib>Gaunt, Trevor</creatorcontrib><creatorcontrib>Kumar, Shankar</creatorcontrib><creatorcontrib>Kiparissi, Fevronia</creatorcontrib><creatorcontrib>Rampling, Dyanne</creatorcontrib><creatorcontrib>Palm, Liina</creatorcontrib><creatorcontrib>Taylor, Stuart A.</creatorcontrib><creatorcontrib>Watson, Tom A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>European radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cococcioni, Lucia</au><au>Fitzke, Heather</au><au>Menys, Alex</au><au>Gaunt, Trevor</au><au>Kumar, Shankar</au><au>Kiparissi, Fevronia</au><au>Rampling, Dyanne</au><au>Palm, Liina</au><au>Taylor, Stuart A.</au><au>Watson, Tom A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Quantitative assessment of terminal ileum motility on MR enterography in Crohn disease: a feasibility study in children</atitle><jtitle>European radiology</jtitle><stitle>Eur Radiol</stitle><addtitle>Eur Radiol</addtitle><date>2021-02-01</date><risdate>2021</risdate><volume>31</volume><issue>2</issue><spage>775</spage><epage>784</epage><pages>775-784</pages><issn>0938-7994</issn><eissn>1432-1084</eissn><abstract>Objectives
Investigate the relationship between quantified terminal ileal (TI) motility and histopathological activity grading, Crohn Disease MRI Index (CDMI) and faecal calprotectin.
Methods
Retrospective review of children with Crohn disease or unclassified inflammatory bowel disease, who underwent MR enterography. Dynamic imaging for 25 patients (median age 12, range 5 to 16) was analysed with a validated motility algorithm. The TI motility score was derived. The primary reference standard was TI Endoscopic biopsy Assessment of Inflammatory Activity (eAIS) within 40 days of the MR enterography. Secondary reference standards: (1) the Crohn Disease MRI Index (CDMI) and (2) faecal calprotectin levels.
Results
MR enterography median motility score was 0.17 a.u. (IQR 0.12 to 0.25; range 0.05 to 0.55), and median CDMI was 3 (IQR 0 to 5.5). Forty-three percent of patients had active disease (eAIS > 0) with a median eAIS score of 0 (IQR 0 to 2; range 0 to 5). The correlation between eAIS and motility was
r
= − 0.58 (
p
= 0.004,
N
= 23). Between CDMI and motility,
r
= − 0.42 (
p
= 0.037,
N
= 25). Motility score was lower in active disease (median 0.12 vs 0.21,
p
= 0.020) while CDMI was higher (median 5 vs 1,
p
= 0.04). In a subset of 12 patients with faecal calprotectin within 3 months of MR enterography, correlation with motility was
r
= − 0.27 (
p
= 0.4).
Conclusions
Quantified terminal ileum motility decreases with increasing histopathological abnormality in children with Crohn disease, reproducing findings in adults. TI motility showed a negative correlation with an MRI activity score but not with faecal calprotectin levels.
Key Points
• It is feasible to perform MRI quantified bowel motility assessment in children using free-breathing techniques.
• Bowel motility in children with Crohn disease decreases as the extent of intestinal inflammation increases.
• Quantified intestinal motility may be a candidate biomarker for treatment efficacy in children with Crohn disease.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>32833090</pmid><doi>10.1007/s00330-020-07084-1</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0938-7994 |
| ispartof | European radiology, 2021-02, Vol.31 (2), p.775-784 |
| issn | 0938-7994 1432-1084 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2436873403 |
| source | MEDLINE; SpringerLink Journals |
| subjects | Adult Algorithms Biomarkers Biopsy Child Children Crohn Disease - diagnostic imaging Diagnostic Radiology Feasibility Studies Humans Ileum Ileum - diagnostic imaging Imaging Inflammatory bowel diseases Internal Medicine Interventional Radiology Intestinal motility Intestine Magnetic Resonance Imaging Medical treatment Medicine Medicine & Public Health Motility Neuroradiology Paediatric Radiology Retrospective Studies Ultrasound |
| title | Quantitative assessment of terminal ileum motility on MR enterography in Crohn disease: a feasibility study in children |
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