Integrative Analysis of Pleomorphic Dermal Sarcomas Reveals Fibroblastic Differentiation and Susceptibility to Immunotherapy

Pleomorphic dermal sarcoma (PDS) is a rare malignant cutaneous tumor with an unknown cell of origin. Locally defined tumors can be treated by curative excisions, whereas advanced stages of the disease are difficult to treat, using standard regimens. We performed whole-exome sequencing on a cohort of...

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Veröffentlicht in:	Clinical cancer research 2020-11, Vol.26 (21), p.5638-5645
Hauptverfasser:	Klein, Sebastian, Quaas, Alexander, Noh, Ka-Won, Cartolano, Maria, Abedpour, Nima, Mauch, Cornelia, Quantius, Jennifer, Reinhardt, Hans Christian, Buettner, Reinhard, Peifer, Martin, Helbig, Doris
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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