Bariatric Surgery Improves Renal Function: a Large Inner-City Population Outcome Study
Background Bariatric surgery is associated with improved renal dysfunction in general population studies. The study examined the effects of bariatric surgery on renal function in a predominantly Hispanic and African American population at a community hospital in New York, USA. Methods This retrospec...
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| Veröffentlicht in: | Obesity surgery 2021, Vol.31 (1), p.260-266 |
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| creator | Saeed, Kashif Ahmed, Leaque Suman, Paritosh Gray, Sanjiv Khan, Khuram DePaz, Hector Persaud, Amrita Fox, Bianca Passos Alothman, Sara Saeed, Saqib |
| description | Background
Bariatric surgery is associated with improved renal dysfunction in general population studies. The study examined the effects of bariatric surgery on renal function in a predominantly Hispanic and African American population at a community hospital in New York, USA.
Methods
This retrospective study analyzed prospectively collected bariatric surgical data from 2247 patients (89% female) who underwent bariatric surgery at a single center. Changes in glomerular filtration rate (eGFR), urine albumin–creatinine ratio (UACR), micro- and macroalbuminuria, and hyperfiltration, which were measured preoperatively and then yearly for 3 years postoperatively, were evaluated with
t
tests and logistic regression analysis, after adjusting for confounding variables. The mean age of the patients at surgery was 37.1 years; the mean preoperative body mass index was 45 ± 7 kg/m
2
.
Results
The results obtained 3 years postoperatively showed the following significant improvements compared with the preoperative values: mean UACR decreased from 40.3 to 11.1 mg/g, mean eGFR improved from 79.4 to 87.3 mL/min, the prevalence of microalbuminuria decreased from 13.7 to 6.2%, the prevalence of macroalbuminuria decreased from 2.5 to 0%, and the prevalence of hyperfiltration decreased from 4.4 to 2.7% (all
P
|
| doi_str_mv | 10.1007/s11695-020-04909-2 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2435755994</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2435755994</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-bb09be6c1e3193d7b0fa1cffa4fcb6ec17aecffa82039b7736c68607e556456c3</originalsourceid><addsrcrecordid>eNp9kEtLAzEQx4MoWh9fwIMEvHhZnSSbZONNi9VCQfF1Ddk0Kyv7qMlG6Lc3tT7Ag6dhmN_8J_khdEjglADIs0CIUDwDChnkClRGN9CISChSS4tNNAIlICsUZTtoN4RXAEoEpdtoh9GCcAL5CD1fGl-bwdcWP0T_4vwST9uF799dwPeuMw2exM4Odd-dY4NnJiF42nXOZ-N6WOK7fhEbsxrj2zjYvnX4YYjz5T7aqkwT3MFX3UNPk6vH8U02u72eji9mmWWSD1lZgiqdsMQxothcllAZYqvK5JUthbNEGrdqCwpMlVIyYUUhQDrORc6FZXvoZJ2bnvwWXRh0WwfrmsZ0ro9B05xxyblSeUKP_6CvffTphytKyoImOSpRdE1Z34fgXaUXvm6NX2oCemVdr63rZF1_Wtc0LR19RceydfOflW_NCWBrIKRRlyz_3v4n9gNBC4zl</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2477822169</pqid></control><display><type>article</type><title>Bariatric Surgery Improves Renal Function: a Large Inner-City Population Outcome Study</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Saeed, Kashif ; Ahmed, Leaque ; Suman, Paritosh ; Gray, Sanjiv ; Khan, Khuram ; DePaz, Hector ; Persaud, Amrita ; Fox, Bianca Passos ; Alothman, Sara ; Saeed, Saqib</creator><creatorcontrib>Saeed, Kashif ; Ahmed, Leaque ; Suman, Paritosh ; Gray, Sanjiv ; Khan, Khuram ; DePaz, Hector ; Persaud, Amrita ; Fox, Bianca Passos ; Alothman, Sara ; Saeed, Saqib</creatorcontrib><description>Background
Bariatric surgery is associated with improved renal dysfunction in general population studies. The study examined the effects of bariatric surgery on renal function in a predominantly Hispanic and African American population at a community hospital in New York, USA.
Methods
This retrospective study analyzed prospectively collected bariatric surgical data from 2247 patients (89% female) who underwent bariatric surgery at a single center. Changes in glomerular filtration rate (eGFR), urine albumin–creatinine ratio (UACR), micro- and macroalbuminuria, and hyperfiltration, which were measured preoperatively and then yearly for 3 years postoperatively, were evaluated with
t
tests and logistic regression analysis, after adjusting for confounding variables. The mean age of the patients at surgery was 37.1 years; the mean preoperative body mass index was 45 ± 7 kg/m
2
.
Results
The results obtained 3 years postoperatively showed the following significant improvements compared with the preoperative values: mean UACR decreased from 40.3 to 11.1 mg/g, mean eGFR improved from 79.4 to 87.3 mL/min, the prevalence of microalbuminuria decreased from 13.7 to 6.2%, the prevalence of macroalbuminuria decreased from 2.5 to 0%, and the prevalence of hyperfiltration decreased from 4.4 to 2.7% (all
P
< .0001). In adjusted multivariate regression analysis, these results remained significant after adjusting for age, sex, race, type of surgery, and presence of diabetes mellitus or hypertension.
Conclusion
In this large study at an inner-city hospital, bariatric surgery was associated with significant improvements in renal dysfunction parameters. These results could assist with informed decisions regarding indications for bariatric surgery.</description><identifier>ISSN: 0960-8923</identifier><identifier>EISSN: 1708-0428</identifier><identifier>DOI: 10.1007/s11695-020-04909-2</identifier><identifier>PMID: 32815104</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Adult ; Albuminuria ; Bariatric Surgery ; Female ; Gastrointestinal surgery ; Glomerular Filtration Rate ; Humans ; Inner city ; Male ; Medicine ; Medicine & Public Health ; New York ; Obesity, Morbid - surgery ; Original Contributions ; Outcome Assessment, Health Care ; Regression analysis ; Renal Insufficiency, Chronic ; Retrospective Studies ; Surgery</subject><ispartof>Obesity surgery, 2021, Vol.31 (1), p.260-266</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2020</rights><rights>Springer Science+Business Media, LLC, part of Springer Nature 2020.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-bb09be6c1e3193d7b0fa1cffa4fcb6ec17aecffa82039b7736c68607e556456c3</citedby><cites>FETCH-LOGICAL-c375t-bb09be6c1e3193d7b0fa1cffa4fcb6ec17aecffa82039b7736c68607e556456c3</cites><orcidid>0000-0002-1509-4447</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11695-020-04909-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11695-020-04909-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32815104$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Saeed, Kashif</creatorcontrib><creatorcontrib>Ahmed, Leaque</creatorcontrib><creatorcontrib>Suman, Paritosh</creatorcontrib><creatorcontrib>Gray, Sanjiv</creatorcontrib><creatorcontrib>Khan, Khuram</creatorcontrib><creatorcontrib>DePaz, Hector</creatorcontrib><creatorcontrib>Persaud, Amrita</creatorcontrib><creatorcontrib>Fox, Bianca Passos</creatorcontrib><creatorcontrib>Alothman, Sara</creatorcontrib><creatorcontrib>Saeed, Saqib</creatorcontrib><title>Bariatric Surgery Improves Renal Function: a Large Inner-City Population Outcome Study</title><title>Obesity surgery</title><addtitle>OBES SURG</addtitle><addtitle>Obes Surg</addtitle><description>Background
Bariatric surgery is associated with improved renal dysfunction in general population studies. The study examined the effects of bariatric surgery on renal function in a predominantly Hispanic and African American population at a community hospital in New York, USA.
Methods
This retrospective study analyzed prospectively collected bariatric surgical data from 2247 patients (89% female) who underwent bariatric surgery at a single center. Changes in glomerular filtration rate (eGFR), urine albumin–creatinine ratio (UACR), micro- and macroalbuminuria, and hyperfiltration, which were measured preoperatively and then yearly for 3 years postoperatively, were evaluated with
t
tests and logistic regression analysis, after adjusting for confounding variables. The mean age of the patients at surgery was 37.1 years; the mean preoperative body mass index was 45 ± 7 kg/m
2
.
Results
The results obtained 3 years postoperatively showed the following significant improvements compared with the preoperative values: mean UACR decreased from 40.3 to 11.1 mg/g, mean eGFR improved from 79.4 to 87.3 mL/min, the prevalence of microalbuminuria decreased from 13.7 to 6.2%, the prevalence of macroalbuminuria decreased from 2.5 to 0%, and the prevalence of hyperfiltration decreased from 4.4 to 2.7% (all
P
< .0001). In adjusted multivariate regression analysis, these results remained significant after adjusting for age, sex, race, type of surgery, and presence of diabetes mellitus or hypertension.
Conclusion
In this large study at an inner-city hospital, bariatric surgery was associated with significant improvements in renal dysfunction parameters. These results could assist with informed decisions regarding indications for bariatric surgery.</description><subject>Adult</subject><subject>Albuminuria</subject><subject>Bariatric Surgery</subject><subject>Female</subject><subject>Gastrointestinal surgery</subject><subject>Glomerular Filtration Rate</subject><subject>Humans</subject><subject>Inner city</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>New York</subject><subject>Obesity, Morbid - surgery</subject><subject>Original Contributions</subject><subject>Outcome Assessment, Health Care</subject><subject>Regression analysis</subject><subject>Renal Insufficiency, Chronic</subject><subject>Retrospective Studies</subject><subject>Surgery</subject><issn>0960-8923</issn><issn>1708-0428</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp9kEtLAzEQx4MoWh9fwIMEvHhZnSSbZONNi9VCQfF1Ddk0Kyv7qMlG6Lc3tT7Ag6dhmN_8J_khdEjglADIs0CIUDwDChnkClRGN9CISChSS4tNNAIlICsUZTtoN4RXAEoEpdtoh9GCcAL5CD1fGl-bwdcWP0T_4vwST9uF799dwPeuMw2exM4Odd-dY4NnJiF42nXOZ-N6WOK7fhEbsxrj2zjYvnX4YYjz5T7aqkwT3MFX3UNPk6vH8U02u72eji9mmWWSD1lZgiqdsMQxothcllAZYqvK5JUthbNEGrdqCwpMlVIyYUUhQDrORc6FZXvoZJ2bnvwWXRh0WwfrmsZ0ro9B05xxyblSeUKP_6CvffTphytKyoImOSpRdE1Z34fgXaUXvm6NX2oCemVdr63rZF1_Wtc0LR19RceydfOflW_NCWBrIKRRlyz_3v4n9gNBC4zl</recordid><startdate>2021</startdate><enddate>2021</enddate><creator>Saeed, Kashif</creator><creator>Ahmed, Leaque</creator><creator>Suman, Paritosh</creator><creator>Gray, Sanjiv</creator><creator>Khan, Khuram</creator><creator>DePaz, Hector</creator><creator>Persaud, Amrita</creator><creator>Fox, Bianca Passos</creator><creator>Alothman, Sara</creator><creator>Saeed, Saqib</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-1509-4447</orcidid></search><sort><creationdate>2021</creationdate><title>Bariatric Surgery Improves Renal Function: a Large Inner-City Population Outcome Study</title><author>Saeed, Kashif ; Ahmed, Leaque ; Suman, Paritosh ; Gray, Sanjiv ; Khan, Khuram ; DePaz, Hector ; Persaud, Amrita ; Fox, Bianca Passos ; Alothman, Sara ; Saeed, Saqib</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-bb09be6c1e3193d7b0fa1cffa4fcb6ec17aecffa82039b7736c68607e556456c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Adult</topic><topic>Albuminuria</topic><topic>Bariatric Surgery</topic><topic>Female</topic><topic>Gastrointestinal surgery</topic><topic>Glomerular Filtration Rate</topic><topic>Humans</topic><topic>Inner city</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>New York</topic><topic>Obesity, Morbid - surgery</topic><topic>Original Contributions</topic><topic>Outcome Assessment, Health Care</topic><topic>Regression analysis</topic><topic>Renal Insufficiency, Chronic</topic><topic>Retrospective Studies</topic><topic>Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Saeed, Kashif</creatorcontrib><creatorcontrib>Ahmed, Leaque</creatorcontrib><creatorcontrib>Suman, Paritosh</creatorcontrib><creatorcontrib>Gray, Sanjiv</creatorcontrib><creatorcontrib>Khan, Khuram</creatorcontrib><creatorcontrib>DePaz, Hector</creatorcontrib><creatorcontrib>Persaud, Amrita</creatorcontrib><creatorcontrib>Fox, Bianca Passos</creatorcontrib><creatorcontrib>Alothman, Sara</creatorcontrib><creatorcontrib>Saeed, Saqib</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>Obesity surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Saeed, Kashif</au><au>Ahmed, Leaque</au><au>Suman, Paritosh</au><au>Gray, Sanjiv</au><au>Khan, Khuram</au><au>DePaz, Hector</au><au>Persaud, Amrita</au><au>Fox, Bianca Passos</au><au>Alothman, Sara</au><au>Saeed, Saqib</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bariatric Surgery Improves Renal Function: a Large Inner-City Population Outcome Study</atitle><jtitle>Obesity surgery</jtitle><stitle>OBES SURG</stitle><addtitle>Obes Surg</addtitle><date>2021</date><risdate>2021</risdate><volume>31</volume><issue>1</issue><spage>260</spage><epage>266</epage><pages>260-266</pages><issn>0960-8923</issn><eissn>1708-0428</eissn><abstract>Background
Bariatric surgery is associated with improved renal dysfunction in general population studies. The study examined the effects of bariatric surgery on renal function in a predominantly Hispanic and African American population at a community hospital in New York, USA.
Methods
This retrospective study analyzed prospectively collected bariatric surgical data from 2247 patients (89% female) who underwent bariatric surgery at a single center. Changes in glomerular filtration rate (eGFR), urine albumin–creatinine ratio (UACR), micro- and macroalbuminuria, and hyperfiltration, which were measured preoperatively and then yearly for 3 years postoperatively, were evaluated with
t
tests and logistic regression analysis, after adjusting for confounding variables. The mean age of the patients at surgery was 37.1 years; the mean preoperative body mass index was 45 ± 7 kg/m
2
.
Results
The results obtained 3 years postoperatively showed the following significant improvements compared with the preoperative values: mean UACR decreased from 40.3 to 11.1 mg/g, mean eGFR improved from 79.4 to 87.3 mL/min, the prevalence of microalbuminuria decreased from 13.7 to 6.2%, the prevalence of macroalbuminuria decreased from 2.5 to 0%, and the prevalence of hyperfiltration decreased from 4.4 to 2.7% (all
P
< .0001). In adjusted multivariate regression analysis, these results remained significant after adjusting for age, sex, race, type of surgery, and presence of diabetes mellitus or hypertension.
Conclusion
In this large study at an inner-city hospital, bariatric surgery was associated with significant improvements in renal dysfunction parameters. These results could assist with informed decisions regarding indications for bariatric surgery.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>32815104</pmid><doi>10.1007/s11695-020-04909-2</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-1509-4447</orcidid></addata></record> |
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| language | eng |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Adult Albuminuria Bariatric Surgery Female Gastrointestinal surgery Glomerular Filtration Rate Humans Inner city Male Medicine Medicine & Public Health New York Obesity, Morbid - surgery Original Contributions Outcome Assessment, Health Care Regression analysis Renal Insufficiency, Chronic Retrospective Studies Surgery |
| title | Bariatric Surgery Improves Renal Function: a Large Inner-City Population Outcome Study |
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