HPLC/ESI-MS identification of diastereomers of Impurity E – Degradation products of cefaclor

•Solid sample of cefaclor stored in room conditions, was analyzed by HPLC/ESI-MS.•As a result of the degradation process, two diastereomers of Impurity E were formed.•The diastereomers are formed due to the isomerization of C6 carbon atom.•The diastereomers have different efficiencies of formation o...

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Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2020-10, Vol.190, p.113533-113533, Article 113533
Hauptverfasser:	Chuchracka, Klaudia, Frański, Rafał, Frańska, Magdalena
Format:	Artikel
Sprache:	eng
Schlagworte:	Cefaclor Degradation Diastereomer Electrospray ionization Impurity E LC/MS
Online-Zugang:	Volltext
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