High HMGA2 expression without gene rearrangement in meningiomas

High mobility group AT‐hook 2 (HMGA2) is a non‐histone transcriptional regulator protein. Aberrant expression of the HMGA2 gene (HMGA2) and structural rearrangement at the chromosomal region 12q14 with HMGA2 involvement have been reported in several mesenchymal tumors. We analyzed truncated and full...

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Veröffentlicht in:	Neuropathology 2020-12, Vol.40 (6), p.540-545
Hauptverfasser:	Nagaishi, Masaya, Nakae, Ryuta, Matsumoto, Yoshiyuki, Fujii, Yoshiko, Sugiura, Yoshiki, Takigawa, Tomoji, Suzuki, Kensuke
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain cancer Brain tumors Cell proliferation chromosomal translocation Fluorescence in situ hybridization Gene rearrangement High mobility group proteins Histones HMGA2 Meningioma mesenchymal tumor Mesenchyme Transcription Tumors
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