Comparison of the effects of losartan, captopril, angiotensin II type 2 receptor agonist compound 21, and MAS receptor agonist AVE 0991 on myocardial ischemia–reperfusion necrosis in rats

Myocardial ischemia may occur as a result of pathophysiological and therapeutical applications such as atherosclerosis, thromboembolism, percutaneous transluminal coronary angioplasty, coronary artery bypass, and transplantation. In this study, we aimed to compare the effects of angiotensin (Ang) II...

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Veröffentlicht in:	Fundamental & clinical pharmacology 2021-08, Vol.35 (4), p.669-680
Hauptverfasser:	Ozhan, Onural, Parlakpinar, Hakan, Acet, Ahmet
Format:	Artikel
Sprache:	eng
Schlagworte:	Agonists Angioplasty Angiotensin Angiotensin II Angiotensin-Converting Enzyme Inhibitors - administration & dosage Angiotensin-Converting Enzyme Inhibitors - pharmacology Animals Arteriosclerosis Atherosclerosis AVE 0991 Captopril Captopril - administration & dosage Captopril - pharmacology compound 21 Coronary artery Coronary vessels Disease Models, Animal Electrocardiography Enzyme inhibitors Heart Rate - drug effects Heart surgery Hemodynamics Imidazoles - administration & dosage Imidazoles - pharmacology Intravenous administration Intravenous infusion Ischemia Life Sciences & Biomedicine losartan Losartan - administration & dosage Losartan - pharmacology Male Myocardial infarction Myocardial ischemia myocardial ischemia–reperfusion injury Myocardial Reperfusion Injury - pathology Myocardial Reperfusion Injury - prevention & control Necrosis Pharmacology Pharmacology & Pharmacy Rats Rats, Wistar Receptors Reperfusion Science & Technology Sulfonamides - administration & dosage Sulfonamides - pharmacology Thiophenes - administration & dosage Thiophenes - pharmacology Thromboembolism Transplantation
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