How synthetic biology can help bioremediation
The World Health Organization reported that “an estimated 12.6 million people died as a result of living or working in an unhealthy environment in 2012, nearly 1 in 4 of total global deaths”. Air, water and soil pollution were the significant risk factors, and there is an urgent need for effective r...
Gespeichert in:
Veröffentlicht in: | Current opinion in chemical biology 2020-10, Vol.58, p.86-95 |
---|---|
Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 95 |
---|---|
container_issue | |
container_start_page | 86 |
container_title | Current opinion in chemical biology |
container_volume | 58 |
creator | Rylott, Elizabeth L. Bruce, Neil C. |
description | The World Health Organization reported that “an estimated 12.6 million people died as a result of living or working in an unhealthy environment in 2012, nearly 1 in 4 of total global deaths”. Air, water and soil pollution were the significant risk factors, and there is an urgent need for effective remediation strategies. But tackling this problem is not easy; there are many different types of pollutants, often widely dispersed, difficult to locate and identify, and in many cases cost-effective clean-up techniques are lacking. Biology offers enormous potential as a tool to develop microbial and plant-based solutions to remediate and restore our environment. Advances in synthetic biology are unlocking this potential enabling the design of tailor-made organisms for bioremediation.
In this article, we showcase examples of xenobiotic clean-up to illustrate current achievements and discuss the limitations to advancing this promising technology to make real-world improvements in the remediation of global pollution.
[Display omitted] |
doi_str_mv | 10.1016/j.cbpa.2020.07.004 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2435192015</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1367593120301009</els_id><sourcerecordid>2435192015</sourcerecordid><originalsourceid>FETCH-LOGICAL-c466t-fb4a96457d27c12e5c9c52702323ad118ee35638fccf66b6de12c566eec0c353</originalsourceid><addsrcrecordid>eNp9kE1Lw0AQhhdRbK3-AQ_So5fE2c8k4EWKWqHgpfclmUzsljQbs6nSf29Cq0dPMwzP-8I8jN1yiDlw87CNsWjzWICAGJIYQJ2xKU-TLAIF4nzYpUkinUk-YVchbAHAiFRfsokUKWil1ZRFS_89D4em31DvcF44X_uPwxzzZr6huh0PHe2odHnvfHPNLqq8DnRzmjO2fnleL5bR6v31bfG0ilAZ00dVofLMKJ2UIkEuSGOGWiQgpJB5yXlKJLWRaYVYGVOYkrhAbQwRAkotZ-z-WNt2_nNPobc7F5DqOm_I74MVSmqeCeAjKo4odj6Ejirbdm6XdwfLwY6W7NaOluxoyUJiB0tD6O7Uvy-G3_4iv1oG4PEI0PDkl6POBnTU4OChI-xt6d1__T_RLXdO</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2435192015</pqid></control><display><type>article</type><title>How synthetic biology can help bioremediation</title><source>Access via ScienceDirect (Elsevier)</source><creator>Rylott, Elizabeth L. ; Bruce, Neil C.</creator><creatorcontrib>Rylott, Elizabeth L. ; Bruce, Neil C.</creatorcontrib><description>The World Health Organization reported that “an estimated 12.6 million people died as a result of living or working in an unhealthy environment in 2012, nearly 1 in 4 of total global deaths”. Air, water and soil pollution were the significant risk factors, and there is an urgent need for effective remediation strategies. But tackling this problem is not easy; there are many different types of pollutants, often widely dispersed, difficult to locate and identify, and in many cases cost-effective clean-up techniques are lacking. Biology offers enormous potential as a tool to develop microbial and plant-based solutions to remediate and restore our environment. Advances in synthetic biology are unlocking this potential enabling the design of tailor-made organisms for bioremediation.
In this article, we showcase examples of xenobiotic clean-up to illustrate current achievements and discuss the limitations to advancing this promising technology to make real-world improvements in the remediation of global pollution.
[Display omitted]</description><identifier>ISSN: 1367-5931</identifier><identifier>EISSN: 1879-0402</identifier><identifier>DOI: 10.1016/j.cbpa.2020.07.004</identifier><identifier>PMID: 32805454</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Bioremediation ; Heavy metals ; Organic pollutants ; Synthetic biology ; Xenobiotics</subject><ispartof>Current opinion in chemical biology, 2020-10, Vol.58, p.86-95</ispartof><rights>2020 Elsevier Ltd</rights><rights>Copyright © 2020 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c466t-fb4a96457d27c12e5c9c52702323ad118ee35638fccf66b6de12c566eec0c353</citedby><cites>FETCH-LOGICAL-c466t-fb4a96457d27c12e5c9c52702323ad118ee35638fccf66b6de12c566eec0c353</cites><orcidid>0000-0002-1609-414X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.cbpa.2020.07.004$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32805454$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rylott, Elizabeth L.</creatorcontrib><creatorcontrib>Bruce, Neil C.</creatorcontrib><title>How synthetic biology can help bioremediation</title><title>Current opinion in chemical biology</title><addtitle>Curr Opin Chem Biol</addtitle><description>The World Health Organization reported that “an estimated 12.6 million people died as a result of living or working in an unhealthy environment in 2012, nearly 1 in 4 of total global deaths”. Air, water and soil pollution were the significant risk factors, and there is an urgent need for effective remediation strategies. But tackling this problem is not easy; there are many different types of pollutants, often widely dispersed, difficult to locate and identify, and in many cases cost-effective clean-up techniques are lacking. Biology offers enormous potential as a tool to develop microbial and plant-based solutions to remediate and restore our environment. Advances in synthetic biology are unlocking this potential enabling the design of tailor-made organisms for bioremediation.
In this article, we showcase examples of xenobiotic clean-up to illustrate current achievements and discuss the limitations to advancing this promising technology to make real-world improvements in the remediation of global pollution.
[Display omitted]</description><subject>Bioremediation</subject><subject>Heavy metals</subject><subject>Organic pollutants</subject><subject>Synthetic biology</subject><subject>Xenobiotics</subject><issn>1367-5931</issn><issn>1879-0402</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp9kE1Lw0AQhhdRbK3-AQ_So5fE2c8k4EWKWqHgpfclmUzsljQbs6nSf29Cq0dPMwzP-8I8jN1yiDlw87CNsWjzWICAGJIYQJ2xKU-TLAIF4nzYpUkinUk-YVchbAHAiFRfsokUKWil1ZRFS_89D4em31DvcF44X_uPwxzzZr6huh0PHe2odHnvfHPNLqq8DnRzmjO2fnleL5bR6v31bfG0ilAZ00dVofLMKJ2UIkEuSGOGWiQgpJB5yXlKJLWRaYVYGVOYkrhAbQwRAkotZ-z-WNt2_nNPobc7F5DqOm_I74MVSmqeCeAjKo4odj6Ejirbdm6XdwfLwY6W7NaOluxoyUJiB0tD6O7Uvy-G3_4iv1oG4PEI0PDkl6POBnTU4OChI-xt6d1__T_RLXdO</recordid><startdate>202010</startdate><enddate>202010</enddate><creator>Rylott, Elizabeth L.</creator><creator>Bruce, Neil C.</creator><general>Elsevier Ltd</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-1609-414X</orcidid></search><sort><creationdate>202010</creationdate><title>How synthetic biology can help bioremediation</title><author>Rylott, Elizabeth L. ; Bruce, Neil C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c466t-fb4a96457d27c12e5c9c52702323ad118ee35638fccf66b6de12c566eec0c353</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Bioremediation</topic><topic>Heavy metals</topic><topic>Organic pollutants</topic><topic>Synthetic biology</topic><topic>Xenobiotics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rylott, Elizabeth L.</creatorcontrib><creatorcontrib>Bruce, Neil C.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Current opinion in chemical biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rylott, Elizabeth L.</au><au>Bruce, Neil C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>How synthetic biology can help bioremediation</atitle><jtitle>Current opinion in chemical biology</jtitle><addtitle>Curr Opin Chem Biol</addtitle><date>2020-10</date><risdate>2020</risdate><volume>58</volume><spage>86</spage><epage>95</epage><pages>86-95</pages><issn>1367-5931</issn><eissn>1879-0402</eissn><abstract>The World Health Organization reported that “an estimated 12.6 million people died as a result of living or working in an unhealthy environment in 2012, nearly 1 in 4 of total global deaths”. Air, water and soil pollution were the significant risk factors, and there is an urgent need for effective remediation strategies. But tackling this problem is not easy; there are many different types of pollutants, often widely dispersed, difficult to locate and identify, and in many cases cost-effective clean-up techniques are lacking. Biology offers enormous potential as a tool to develop microbial and plant-based solutions to remediate and restore our environment. Advances in synthetic biology are unlocking this potential enabling the design of tailor-made organisms for bioremediation.
In this article, we showcase examples of xenobiotic clean-up to illustrate current achievements and discuss the limitations to advancing this promising technology to make real-world improvements in the remediation of global pollution.
[Display omitted]</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>32805454</pmid><doi>10.1016/j.cbpa.2020.07.004</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0002-1609-414X</orcidid><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1367-5931 |
ispartof | Current opinion in chemical biology, 2020-10, Vol.58, p.86-95 |
issn | 1367-5931 1879-0402 |
language | eng |
recordid | cdi_proquest_miscellaneous_2435192015 |
source | Access via ScienceDirect (Elsevier) |
subjects | Bioremediation Heavy metals Organic pollutants Synthetic biology Xenobiotics |
title | How synthetic biology can help bioremediation |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T19%3A24%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=How%20synthetic%20biology%20can%20help%20bioremediation&rft.jtitle=Current%20opinion%20in%20chemical%20biology&rft.au=Rylott,%20Elizabeth%20L.&rft.date=2020-10&rft.volume=58&rft.spage=86&rft.epage=95&rft.pages=86-95&rft.issn=1367-5931&rft.eissn=1879-0402&rft_id=info:doi/10.1016/j.cbpa.2020.07.004&rft_dat=%3Cproquest_cross%3E2435192015%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2435192015&rft_id=info:pmid/32805454&rft_els_id=S1367593120301009&rfr_iscdi=true |