Extensively drug-resistant Acinetobacter baumannii carrying blaOXA-23-like and armA in a hospital after an intervention in the intensive care unit which ended a long-standing endemicity
The aim of the study was to evaluate for a long time the effectiveness of an intervention designed to reduce carbapenem-resistant Acinetobacter baumannii (CRAB) and its impact on colistin usage in the ICU of a tertiary hospital in Spain. The rate of carbapenem resistance declined drastically during...
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| Veröffentlicht in: | European journal of clinical microbiology & infectious diseases 2021-02, Vol.40 (2), p.385-389 |
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| container_title | European journal of clinical microbiology & infectious diseases |
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| creator | Rodríguez-Lucas, Carlos Rodicio, M. Rosario Vázquez, Xenia Escudero, Dolores Quindós, Brígida Alaguero, Miguel Fernández, Javier |
| description | The aim of the study was to evaluate for a long time the effectiveness of an intervention designed to reduce carbapenem-resistant
Acinetobacter baumannii
(CRAB) and its impact on colistin usage in the ICU of a tertiary hospital in Spain. The rate of carbapenem resistance declined drastically during the period of study (2015 to 2018), from 93.57 to 74.65%, especially in the ICU. A significant decrease in colistin usage, from 1.16 to 0.39 DOTs, was observed. Forty-nine CRAB isolates recovered nearly 1 year after starting the intervention were characterized. Most of them were recovered from patients admitted in wards other than ICU and were extensively drug-resistant, carried
bla
OXA-23-like
and
armA
, and belonged to ST218. Implementation of control measures is crucial to CRAB control in ICUs but must be extended to all wards in order to eradicate CRAB from hospitals. |
| doi_str_mv | 10.1007/s10096-020-04009-0 |
| format | Article |
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Acinetobacter baumannii
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Acinetobacter baumannii
(CRAB) and its impact on colistin usage in the ICU of a tertiary hospital in Spain. The rate of carbapenem resistance declined drastically during the period of study (2015 to 2018), from 93.57 to 74.65%, especially in the ICU. A significant decrease in colistin usage, from 1.16 to 0.39 DOTs, was observed. Forty-nine CRAB isolates recovered nearly 1 year after starting the intervention were characterized. Most of them were recovered from patients admitted in wards other than ICU and were extensively drug-resistant, carried
bla
OXA-23-like
and
armA
, and belonged to ST218. 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Acinetobacter baumannii
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bla
OXA-23-like
and
armA
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| fulltext | fulltext |
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| ispartof | European journal of clinical microbiology & infectious diseases, 2021-02, Vol.40 (2), p.385-389 |
| issn | 0934-9723 1435-4373 |
| language | eng |
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| source | SpringerNature Journals |
| subjects | Acinetobacter baumannii Antibiotics Biomedical and Life Sciences Biomedicine Brief Report Colistin Drug resistance Internal Medicine Medical Microbiology |
| title | Extensively drug-resistant Acinetobacter baumannii carrying blaOXA-23-like and armA in a hospital after an intervention in the intensive care unit which ended a long-standing endemicity |
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