Influence of hematoma volume and age on cognitive functions and ADL after putaminal hemorrhage

•Effects of age and hematoma size on the cognitive functions (RCPM and MMSE) and ADL (FIM–Motor) at discharge after putaminal hemorrhage were investigated.•Cognitive functions and ADL depended on the hematoma size and age of the patients.•The trend in the RCPM score was more representative of the FIM-Motor score than that in the MMSE score.•MMSE is commonly used in clinical practice, but RCPM might be recommended for evaluating the ADL outcome. After cerebral hemorrhage, cognitive functions and activities of daily living (ADL) are affected by various factors, including hematoma volume and patient age. In the present study, we investigated the effect of age and hematoma volume on cognitive functions and on ADL. The sample comprised 274 patients (183 men and 91 women; mean age 58.2 ± 12.5 years) with putaminal hemorrhage who were hospitalized in a convalescent rehabilitation ward. Hematoma volume was estimated from computed tomography imaging at stroke onset. Cognitive functions were evaluated using Raven's Colored Progressive Matrices test (RCPM) and the Mini-Mental State Examination (MMSE) at hospital admission, while ADL score was assessed at discharge using the Functional Independence Measure motor subscale (FIM-M). In the present study, we classified the patients into six groups according to whether they were non-elderly or elderly (cutoff age, 60 years) and whether their hematoma was small, medium, or large (cutoff volumes, 20 and 40 mL, respectively). Subsequently, the scores on the RCPM, MMSE, and FIM-M were compared among the groups. In both age groups, patients with a larger hematoma volume had lower RCPM and MMSE scores. Patients