Acute myeloid leukemia with myelodysplasia-related changes diagnosed with multilineage dysplasia alone demonstrates a superior clinical outcome

Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) generally confers poor prognosis; however, the clinical outcome remains heterogeneous. We sought to further stratify this subentity of AML by performing a retrospective analysis of 179 adult patients with AML-MRC diagnosed at our i...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Human pathology 2020-10, Vol.104, p.117-126
Hauptverfasser:	Jiang, Gina, Capo-Chichi, Jose-Mario, Liu, Aijun, Atenafu, Eshetu G., Guo, Robert, Tierens, Ann, Minden, Mark D., Chang, Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute myeloid leukemia Adult Age Aged Aged, 80 and over ASXL1 mutation Biomarkers, Tumor - genetics Bone marrow Cell Lineage Classification Clinical outcome Clinical outcomes Cytogenetics Female Genetic Predisposition to Disease Hematopoietic Stem Cell Transplantation - adverse effects Hematopoietic Stem Cell Transplantation - mortality Humans Leukemia Leukemia, Myeloid, Acute - genetics Leukemia, Myeloid, Acute - mortality Leukemia, Myeloid, Acute - pathology Leukemia, Myeloid, Acute - surgery Male Medical prognosis Middle Aged Multilineage dysplasia Mutation Myelodysplasia-related changes Myelodysplastic syndromes Myelodysplastic Syndromes - genetics Myelodysplastic Syndromes - mortality Myelodysplastic Syndromes - pathology Myelodysplastic Syndromes - surgery NPM1 mutation Nuclear Proteins - genetics Patients Progression-Free Survival Repressor Proteins - genetics Retrospective Studies Risk Assessment Risk Factors Time Factors Transplants & implants Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!