Feasibility and performance of a novel probe panel to detect somatic DNA copy number alterations in clinical specimens for predicting prostate cancer progression

Background To assess the feasibility of a novel DNA‐based probe panel to detect copy number alterations (CNAs) in prostate tumor DNA and its performance for predicting clinical progression. Methods A probe panel was developed and optimized to measure CNAs in trace amounts of tumor DNA (2 ng) isolate...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Prostate 2020-10, Vol.80 (14), p.1253-1262
Hauptverfasser:	Liu, Wennuan, Hou, Jun, Petkewicz, Jacqueline, Na, Rong, Wang, Chi‐Hsiung, Sun, Jishan, Gallagher, Johnie, Bogachkov, Yedida Y., Swenson, Laura, Regner, MaryAnn, Resurreccion, W. Kyle, Isaacs, William B., Brendler, Charles B., Crawford, Susan, Zheng, S. Lilly, Helfand, Brian T., Xu, Jianfeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biopsy BRCA2 protein Copy number Deoxyribonucleic acid Diagnosis Disease Progression DNA DNA Probes - genetics DNA, Neoplasm - genetics Feasibility Studies Gene Dosage Humans Male Metastases Middle Aged Myc protein Paraffin Patients Predictive Value of Tests probe panel Prostate cancer prostate cancer progression Prostatectomy Prostatic Neoplasms - genetics Prostatic Neoplasms - pathology PTEN protein somatic CNA Surgery
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!