Cold-induced Yes-associated-protein expression through miR-429 mediates the browning of white adipose tissue

Targeting the white-to-brown fat conversion is important for developing potential strategies to counteract metabolic diseases; yet the mechanisms are not fully understood. Yes-associated-protein (YAP), a transcription co-activator, was demonstrated to regulate adipose tissue functions; however, its...

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Veröffentlicht in:Science China. Life sciences 2021-03, Vol.64 (3), p.404-418
Hauptverfasser: Ye, Chenji, Duan, Jinjie, Zhang, Xuejiao, Yao, Liu, Song, Yayue, Wang, Guangyan, Li, Qi, Wang, Biqing, Ai, Ding, Wang, Chunjiong, Zhu, Yi
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