Novel ex vivo disease model for extramammary Paget’s disease using the cancer tissue-originated spheroid method

•Effective EMPD treatments are lacking partly because of no current ex vivo models.•We firstly established CTOSs, an ex vivo model of EMPD.•CTOSs retain the characteristics of original tumors.•CTOSs are useful for investigating the pathogenesis and treatments of EMPD. Extramammary Paget’s disease (E...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of dermatological science 2020-09, Vol.99 (3), p.185-192
Hauptverfasser:	Arita, Takahiro, Kondo, Jumpei, Kaneko, Yuka, Tsutsumi, Miho, Kanemaru, Mai, Matsui, Mari, Arakawa, Yukiyasu, Katoh, Norito, Inoue, Masahiro, Asai, Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemosensitivity assay CTOS Ex vivo disease model Extramammary Paget’s disease HRG–HER3 signaling
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!