Glioneuronal Hamartomas in the Central Nervous System of Two Goats

Two goats (6 months old and 5 years old) were evaluated for neurological signs including laboured breathing, stiffness and obtundation. Solitary masses were noted in the brainstem and spinal cord, respectively. Histopathology of both cases revealed the lesions were composed of a mixture of glial and...

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Veröffentlicht in:Journal of comparative pathology 2020-07, Vol.178, p.10-15
Hauptverfasser: Wu, T., Miller, A., Jager, M., Southard, T.
Format: Artikel
Sprache:eng
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Zusammenfassung:Two goats (6 months old and 5 years old) were evaluated for neurological signs including laboured breathing, stiffness and obtundation. Solitary masses were noted in the brainstem and spinal cord, respectively. Histopathology of both cases revealed the lesions were composed of a mixture of glial and neuronal cells, consistent with glioneuronal hamartomas. The cause of death was attributed to the mass in the 6-month-old, while the cause of death in the 5-year-old was attributed to listeriosis. Hamartomas of neural origin are rarely described in veterinary species, and this report represents the first report of glioneuronal hamartomas in goats.
ISSN:0021-9975
1532-3129
DOI:10.1016/j.jcpa.2020.06.003