Colonization by multidrug-resistant microorganisms of hospitalized newborns and their mothers in the neonatal unit context
The mother plays a fundamental role in the constitution and regulation of her child's healthy microbiota, however, preterm newborns are separated from their mothers soon after birth and transferred to Neonatal Intensive Care Units, being exposed the constant risk for the development of multidru...
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| Veröffentlicht in: | Journal of infection in developing countries 2020-07, Vol.14 (7), p.765-771 |
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| creator | Sakai, Andressa Midori Iensue, Thayla Nadrielly Aparecida Nicolino Pereira, Kauana Olanda De Souza, Nathália Aparecida Andrade Silva, Claudineia Maria Salvador, Marta Silva de Almeida Rodrigues, Renne Capobiango, Jaqueline Dario Pelisson, Marsileni Vespero, Eliana Carolina Lioni, Lucy Megumi Yamauchi Perugini, Marcia Regina Eches Ogatta, Sueli Fumie Yamada Rossetto, Edilaine Giovanini Kerbauy, Gilselena |
| description | The mother plays a fundamental role in the constitution and regulation of her child's healthy microbiota, however, preterm newborns are separated from their mothers soon after birth and transferred to Neonatal Intensive Care Units, being exposed the constant risk for the development of multidrug-resistant microorganisms' infections. The aim of this study was to explore the multidrug-resistant microorganism colonization of hospitalized babies and their mothers in the neonatal unit context.
A prospective case study conducted with hospitalized babies and their mothers in the Neonatal Unit at a university hospital. The sample was composed of 433 binomials (mother-child). Colonization culture samples were taken at the moment of the baby's discharge, via two swabs in the oral, nasal, axillary, inguinal, and rectal regions.
The colonization incidence among the binomials, 30 (6.9%) were both colonized by multi-resistant microorganisms. Mothers of colonized babies (24.4%) demonstrated a higher chance of colonization in comparison to mothers of non-colonized babies (11.9%) (p = 0.002). Relationships were drawn between baby colonization and prematurity, extremely low birth weight, and non-exclusive maternal breastfeeding (p |
| doi_str_mv | 10.3855/jidc.12091 |
| format | Article |
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A prospective case study conducted with hospitalized babies and their mothers in the Neonatal Unit at a university hospital. The sample was composed of 433 binomials (mother-child). Colonization culture samples were taken at the moment of the baby's discharge, via two swabs in the oral, nasal, axillary, inguinal, and rectal regions.
The colonization incidence among the binomials, 30 (6.9%) were both colonized by multi-resistant microorganisms. Mothers of colonized babies (24.4%) demonstrated a higher chance of colonization in comparison to mothers of non-colonized babies (11.9%) (p = 0.002). Relationships were drawn between baby colonization and prematurity, extremely low birth weight, and non-exclusive maternal breastfeeding (p<0.05). ESBL-producing Gram-negative microorganisms were more frequent in the cultures of the binomials, with 35.9% of the babies colonized with Klebsiella spp. ESBL and 42.0% of the mothers with Escherichia coli ESBL. Furthermore, 50% of the binomials were colonized with E. coli ESBL.
The prematurity, extremely low birth weight, and non-exclusive breastfeeding at hospital discharge were associated with baby colonization by multidrug-resistant microorganism. Furthermore, mothers of colonized children presented higher chances of colonization.</description><identifier>ISSN: 1972-2680</identifier><identifier>ISSN: 2036-6590</identifier><identifier>EISSN: 1972-2680</identifier><identifier>DOI: 10.3855/jidc.12091</identifier><identifier>PMID: 32794468</identifier><language>eng</language><publisher>Italy: Journal of Infection in Developing Countries</publisher><subject>Babies ; Birth weight ; Breastfeeding & lactation ; Drug resistance ; Hospitalization ; Microorganisms ; Mothers ; Multidrug resistant organisms ; Newborn babies</subject><ispartof>Journal of infection in developing countries, 2020-07, Vol.14 (7), p.765-771</ispartof><rights>Copyright (c) 2020 Andressa Midori Sakai, Thayla Nadrielly Aparecida Nicolino Iensue, Kauana Olanda Pereira, Nathália Aparecida Andrade de Souza, Claudineia Maria Silva, Marta Silva de Almeida Salvador, Renne Rodrigues, Jaqueline Dario Capobiango, Marsileni Pelisson, Eliana Carolina Vespero, Lucy Megumi Yamauchi Lioni, Marcia Regina Eches Perugini, Sueli Fumie Yamada Ogatta, Edilaine Giovanini Rossetto, Gilselena Kerbauy.</rights><rights>2020. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c315t-67c968f1245260bb716c4c1227fa24d4c059f5690f4afef0ffd48e5c4828b9d3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27907,27908</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32794468$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sakai, Andressa Midori</creatorcontrib><creatorcontrib>Iensue, Thayla Nadrielly Aparecida Nicolino</creatorcontrib><creatorcontrib>Pereira, Kauana Olanda</creatorcontrib><creatorcontrib>De Souza, Nathália Aparecida Andrade</creatorcontrib><creatorcontrib>Silva, Claudineia Maria</creatorcontrib><creatorcontrib>Salvador, Marta Silva de Almeida</creatorcontrib><creatorcontrib>Rodrigues, Renne</creatorcontrib><creatorcontrib>Capobiango, Jaqueline Dario</creatorcontrib><creatorcontrib>Pelisson, Marsileni</creatorcontrib><creatorcontrib>Vespero, Eliana Carolina</creatorcontrib><creatorcontrib>Lioni, Lucy Megumi Yamauchi</creatorcontrib><creatorcontrib>Perugini, Marcia Regina Eches</creatorcontrib><creatorcontrib>Ogatta, Sueli Fumie Yamada</creatorcontrib><creatorcontrib>Rossetto, Edilaine Giovanini</creatorcontrib><creatorcontrib>Kerbauy, Gilselena</creatorcontrib><title>Colonization by multidrug-resistant microorganisms of hospitalized newborns and their mothers in the neonatal unit context</title><title>Journal of infection in developing countries</title><addtitle>J Infect Dev Ctries</addtitle><description>The mother plays a fundamental role in the constitution and regulation of her child's healthy microbiota, however, preterm newborns are separated from their mothers soon after birth and transferred to Neonatal Intensive Care Units, being exposed the constant risk for the development of multidrug-resistant microorganisms' infections. The aim of this study was to explore the multidrug-resistant microorganism colonization of hospitalized babies and their mothers in the neonatal unit context.
A prospective case study conducted with hospitalized babies and their mothers in the Neonatal Unit at a university hospital. The sample was composed of 433 binomials (mother-child). Colonization culture samples were taken at the moment of the baby's discharge, via two swabs in the oral, nasal, axillary, inguinal, and rectal regions.
The colonization incidence among the binomials, 30 (6.9%) were both colonized by multi-resistant microorganisms. Mothers of colonized babies (24.4%) demonstrated a higher chance of colonization in comparison to mothers of non-colonized babies (11.9%) (p = 0.002). Relationships were drawn between baby colonization and prematurity, extremely low birth weight, and non-exclusive maternal breastfeeding (p<0.05). ESBL-producing Gram-negative microorganisms were more frequent in the cultures of the binomials, with 35.9% of the babies colonized with Klebsiella spp. ESBL and 42.0% of the mothers with Escherichia coli ESBL. Furthermore, 50% of the binomials were colonized with E. coli ESBL.
The prematurity, extremely low birth weight, and non-exclusive breastfeeding at hospital discharge were associated with baby colonization by multidrug-resistant microorganism. 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The aim of this study was to explore the multidrug-resistant microorganism colonization of hospitalized babies and their mothers in the neonatal unit context.
A prospective case study conducted with hospitalized babies and their mothers in the Neonatal Unit at a university hospital. The sample was composed of 433 binomials (mother-child). Colonization culture samples were taken at the moment of the baby's discharge, via two swabs in the oral, nasal, axillary, inguinal, and rectal regions.
The colonization incidence among the binomials, 30 (6.9%) were both colonized by multi-resistant microorganisms. Mothers of colonized babies (24.4%) demonstrated a higher chance of colonization in comparison to mothers of non-colonized babies (11.9%) (p = 0.002). Relationships were drawn between baby colonization and prematurity, extremely low birth weight, and non-exclusive maternal breastfeeding (p<0.05). ESBL-producing Gram-negative microorganisms were more frequent in the cultures of the binomials, with 35.9% of the babies colonized with Klebsiella spp. ESBL and 42.0% of the mothers with Escherichia coli ESBL. Furthermore, 50% of the binomials were colonized with E. coli ESBL.
The prematurity, extremely low birth weight, and non-exclusive breastfeeding at hospital discharge were associated with baby colonization by multidrug-resistant microorganism. Furthermore, mothers of colonized children presented higher chances of colonization.</abstract><cop>Italy</cop><pub>Journal of Infection in Developing Countries</pub><pmid>32794468</pmid><doi>10.3855/jidc.12091</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| issn | 1972-2680 2036-6590 1972-2680 |
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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Babies Birth weight Breastfeeding & lactation Drug resistance Hospitalization Microorganisms Mothers Multidrug resistant organisms Newborn babies |
| title | Colonization by multidrug-resistant microorganisms of hospitalized newborns and their mothers in the neonatal unit context |
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