MiR‐134‐5p targeting XIAP modulates oxidative stress and apoptosis in cardiomyocytes under hypoxia/reperfusion‐induced injury

MicroRNA‐134‐5p (MiR‐134‐5p) has been proposed as a promising novel biomarker for the diagnosis of acute myocardial infarction (AMI). However, the biological role of miR‐134‐5p in ischemic cardiomyocytes has been little disclosed yet. Expression of miR‐134‐5p and X‐linked inhibitor of apoptosis prot...

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Veröffentlicht in:	IUBMB life 2020-10, Vol.72 (10), p.2154-2166
Hauptverfasser:	Lu, Min, Qin, Xinglei, Yao, Jungong, Yang, Yuanyuan, Zhao, Minghu, Sun, Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	AMI Apoptosis Biphenyl Cardiomyocytes Cell viability Enzymes Flow cytometry Glutathione peroxidase Hypoxia IAP protein Ischemia Malondialdehyde miRNA miR‐134‐5p Myocardial infarction Oxidation Oxidative stress oxidative stress, apoptosis Reperfusion Superoxide dismutase XIAP XIAP protein
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