NHEJ inhibitor SCR7 and its different forms: Promising CRISPR tools for genome engineering

The CRISPR-Cas system currently stands as one of the best multifaceted tools for site-specific genome engineering in mammals. An important aspect of research in this field focusses on improving the specificity and efficacy of precise genome editing in multiple model systems. The cornerstone of this...

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Veröffentlicht in:	Gene 2020-12, Vol.763, p.144997-144997, Article 144997
Hauptverfasser:	Ray, Ujjayinee, Vartak, Supriya V., Raghavan, Sathees C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Double-strand break DSB Repair Genome editing Immunodeficiency Ligase IV Nonhomologous DNA end joining
Online-Zugang:	Volltext
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