Detachable Nanoparticle-Enhanced Chemoimmunotherapy Based on Precise Killing of Tumor Seeds and Normalizing the Growing Soil Strategy

Although immunogenic cell death (ICD)-based chemoimmunotherapy elicits an immune response, it always focuses on eliminating “seeds” (tumor cells) but neglects “soil” (tumor microenvironment, TME), leading to tumor growth and metastasis. Herein, a type of detachable core–shell nanoplatform (DOX@HA-MM...

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Veröffentlicht in:	Nano letters 2020-09, Vol.20 (9), p.6272-6280
Hauptverfasser:	Wang, Lei, Ding, Kaili, Zheng, Cuixia, Xiao, Huifang, Liu, Xinxin, Sun, Lingling, Omer, Rida, Feng, Qianhua, Zhang, Zhenzhong
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Death Doxorubicin Immunotherapy Matrix Metalloproteinase 2 Nanoparticles Neoplasm Seeding Neoplasms - therapy Tumor Microenvironment
Online-Zugang:	Volltext
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