Factors Associated with Nonsuppression of HIV Infection in the Spanish VACH Cohort
We aim to determine the prevalence of HIV nonsuppression and factors associated with it. This is a cross-sectional multicenter study carried out in January 2016 with data of the VACH Cohort, a registry participated by 23 hospitals from most regions of Spain. The prevalence of HIV nonsuppression, def...
Gespeichert in:
| Veröffentlicht in: | AIDS research and human retroviruses 2020-11, Vol.36 (11), p.927-932 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 932 |
|---|---|
| container_issue | 11 |
| container_start_page | 927 |
| container_title | AIDS research and human retroviruses |
| container_volume | 36 |
| creator | Roca, Bernardino Teira, R Domingo, P Geijo, P Galindo, MJ Lozano, F Terron, A Garrido, M Suarez-Lozano, I Vidal, F Muñoz-Sanchez, P Viciana, P Ribera, E Castaño, M Martinez, E Puig, T Estrada, V Deig, E de la Fuente, B Montero, M Muñoz-Sanz, A Sanchez, T Romero-Palacios, A Lacalle, JR |
| description | We aim to determine the prevalence of HIV nonsuppression and factors associated with it. This is a cross-sectional multicenter study carried out in January 2016 with data of the VACH Cohort, a registry participated by 23 hospitals from most regions of Spain. The prevalence of HIV nonsuppression, defined as HIV RNA ≥200 copies/mL, is documented. The possible association of HIV nonsuppression with sociodemographic and clinical variables is assessed with a logistic regression analysis. A total of 30,843 adult patients are included; 7,358 of them (23.86%) have nonsuppressed HIV. An association is found between nonsuppression of HIV and the following variables: lower body mass index, lower age of patients in their last registered visit, lower number of visits carried out during follow-up, lower last available CD4 cell count, higher age of patients at the time of their HIV infection diagnosis, higher lowest available CD4 cell count, higher highest available HIV RNA, enrolment in the Cohort in first years of the HIV epidemic, region of Spain where the patient is attended other than Andalusia, HIV risk factor other than sexual, occurrence of death during follow-up, hepatitis C coinfection, being a smoker, pertaining to groups A1 or A2 of the CDC groups classification, and not taking antiretroviral treatment, p |
| doi_str_mv | 10.1089/aid.2020.0016 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2432865457</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2460087426</sourcerecordid><originalsourceid>FETCH-LOGICAL-c254t-618663e1d40a1ff6f604ccf38b939b5f62614895209e642296c93a6feaaae06e3</originalsourceid><addsrcrecordid>eNpdkEtLAzEYRYMoWKtL9wE3bqZ-eUyaLMtgbUEUfHQb0jRhUtrJmMwg_ntnqCtXFy6Hy-UgdEtgRkCqBxN2MwoUZgBEnKEJUYwUkkN5jiYgpSoopeoSXeW8BwBFaTlBb0tju5gyXuQcbTCd2-Hv0NX4JTa5b9vkcg6xwdHj1XqD1413thuL0OCudvi9NU3INd4sqhWuYh1Td40uvDlkd_OXU_S5fPyoVsXz69O6WjwXlpa8KwSRQjBHdhwM8V54Adxaz-RWMbUtvaCCcKlKCsoJPjwXVjEjvDPGOBCOTdH9abdN8at3udPHkK07HEzjYp815YxKUfJyPqB3_9B97FMzvBsoASDnnIqBKk6UTTHn5LxuUzia9KMJ6NGwHgzr0bAeDbNfUK1ssQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2460087426</pqid></control><display><type>article</type><title>Factors Associated with Nonsuppression of HIV Infection in the Spanish VACH Cohort</title><source>Alma/SFX Local Collection</source><creator>Roca, Bernardino ; Teira, R ; Domingo, P ; Geijo, P ; Galindo, MJ ; Lozano, F ; Terron, A ; Garrido, M ; Suarez-Lozano, I ; Vidal, F ; Muñoz-Sanchez, P ; Viciana, P ; Ribera, E ; Castaño, M ; Martinez, E ; Puig, T ; Estrada, V ; Deig, E ; de la Fuente, B ; Montero, M ; Muñoz-Sanz, A ; Sanchez, T ; Romero-Palacios, A ; Lacalle, JR</creator><creatorcontrib>Roca, Bernardino ; Teira, R ; Domingo, P ; Geijo, P ; Galindo, MJ ; Lozano, F ; Terron, A ; Garrido, M ; Suarez-Lozano, I ; Vidal, F ; Muñoz-Sanchez, P ; Viciana, P ; Ribera, E ; Castaño, M ; Martinez, E ; Puig, T ; Estrada, V ; Deig, E ; de la Fuente, B ; Montero, M ; Muñoz-Sanz, A ; Sanchez, T ; Romero-Palacios, A ; Lacalle, JR ; on Behalf of the Spanish VACH Cohort Group</creatorcontrib><description>We aim to determine the prevalence of HIV nonsuppression and factors associated with it. This is a cross-sectional multicenter study carried out in January 2016 with data of the VACH Cohort, a registry participated by 23 hospitals from most regions of Spain. The prevalence of HIV nonsuppression, defined as HIV RNA ≥200 copies/mL, is documented. The possible association of HIV nonsuppression with sociodemographic and clinical variables is assessed with a logistic regression analysis. A total of 30,843 adult patients are included; 7,358 of them (23.86%) have nonsuppressed HIV. An association is found between nonsuppression of HIV and the following variables: lower body mass index, lower age of patients in their last registered visit, lower number of visits carried out during follow-up, lower last available CD4 cell count, higher age of patients at the time of their HIV infection diagnosis, higher lowest available CD4 cell count, higher highest available HIV RNA, enrolment in the Cohort in first years of the HIV epidemic, region of Spain where the patient is attended other than Andalusia, HIV risk factor other than sexual, occurrence of death during follow-up, hepatitis C coinfection, being a smoker, pertaining to groups A1 or A2 of the CDC groups classification, and not taking antiretroviral treatment, p < .001 in all cases. HIV nonsuppression is still common with the effective antiretroviral treatment nowadays available. HIV nonsuppression is associated with HIV risk factor other than sexual, hepatitis C coinfection, and being a smoker, among other factors.</description><identifier>ISSN: 0889-2229</identifier><identifier>EISSN: 1931-8405</identifier><identifier>DOI: 10.1089/aid.2020.0016</identifier><language>eng</language><publisher>New Rochelle: Mary Ann Liebert, Inc</publisher><subject>AIDS/HIV ; Antiretroviral agents ; Body mass ; Body mass index ; Body size ; CD4 antigen ; Epidemics ; Health risks ; Health services ; Hepatitis ; Hepatitis C ; HIV ; Human immunodeficiency virus ; Infections ; Patients ; Public health ; Regression analysis ; Ribonucleic acid ; Risk analysis ; Risk factors ; RNA ; Sexually transmitted diseases ; STD</subject><ispartof>AIDS research and human retroviruses, 2020-11, Vol.36 (11), p.927-932</ispartof><rights>Copyright Mary Ann Liebert, Inc. Nov 2020</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c254t-618663e1d40a1ff6f604ccf38b939b5f62614895209e642296c93a6feaaae06e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Roca, Bernardino</creatorcontrib><creatorcontrib>Teira, R</creatorcontrib><creatorcontrib>Domingo, P</creatorcontrib><creatorcontrib>Geijo, P</creatorcontrib><creatorcontrib>Galindo, MJ</creatorcontrib><creatorcontrib>Lozano, F</creatorcontrib><creatorcontrib>Terron, A</creatorcontrib><creatorcontrib>Garrido, M</creatorcontrib><creatorcontrib>Suarez-Lozano, I</creatorcontrib><creatorcontrib>Vidal, F</creatorcontrib><creatorcontrib>Muñoz-Sanchez, P</creatorcontrib><creatorcontrib>Viciana, P</creatorcontrib><creatorcontrib>Ribera, E</creatorcontrib><creatorcontrib>Castaño, M</creatorcontrib><creatorcontrib>Martinez, E</creatorcontrib><creatorcontrib>Puig, T</creatorcontrib><creatorcontrib>Estrada, V</creatorcontrib><creatorcontrib>Deig, E</creatorcontrib><creatorcontrib>de la Fuente, B</creatorcontrib><creatorcontrib>Montero, M</creatorcontrib><creatorcontrib>Muñoz-Sanz, A</creatorcontrib><creatorcontrib>Sanchez, T</creatorcontrib><creatorcontrib>Romero-Palacios, A</creatorcontrib><creatorcontrib>Lacalle, JR</creatorcontrib><creatorcontrib>on Behalf of the Spanish VACH Cohort Group</creatorcontrib><title>Factors Associated with Nonsuppression of HIV Infection in the Spanish VACH Cohort</title><title>AIDS research and human retroviruses</title><description>We aim to determine the prevalence of HIV nonsuppression and factors associated with it. This is a cross-sectional multicenter study carried out in January 2016 with data of the VACH Cohort, a registry participated by 23 hospitals from most regions of Spain. The prevalence of HIV nonsuppression, defined as HIV RNA ≥200 copies/mL, is documented. The possible association of HIV nonsuppression with sociodemographic and clinical variables is assessed with a logistic regression analysis. A total of 30,843 adult patients are included; 7,358 of them (23.86%) have nonsuppressed HIV. An association is found between nonsuppression of HIV and the following variables: lower body mass index, lower age of patients in their last registered visit, lower number of visits carried out during follow-up, lower last available CD4 cell count, higher age of patients at the time of their HIV infection diagnosis, higher lowest available CD4 cell count, higher highest available HIV RNA, enrolment in the Cohort in first years of the HIV epidemic, region of Spain where the patient is attended other than Andalusia, HIV risk factor other than sexual, occurrence of death during follow-up, hepatitis C coinfection, being a smoker, pertaining to groups A1 or A2 of the CDC groups classification, and not taking antiretroviral treatment, p < .001 in all cases. HIV nonsuppression is still common with the effective antiretroviral treatment nowadays available. HIV nonsuppression is associated with HIV risk factor other than sexual, hepatitis C coinfection, and being a smoker, among other factors.</description><subject>AIDS/HIV</subject><subject>Antiretroviral agents</subject><subject>Body mass</subject><subject>Body mass index</subject><subject>Body size</subject><subject>CD4 antigen</subject><subject>Epidemics</subject><subject>Health risks</subject><subject>Health services</subject><subject>Hepatitis</subject><subject>Hepatitis C</subject><subject>HIV</subject><subject>Human immunodeficiency virus</subject><subject>Infections</subject><subject>Patients</subject><subject>Public health</subject><subject>Regression analysis</subject><subject>Ribonucleic acid</subject><subject>Risk analysis</subject><subject>Risk factors</subject><subject>RNA</subject><subject>Sexually transmitted diseases</subject><subject>STD</subject><issn>0889-2229</issn><issn>1931-8405</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNpdkEtLAzEYRYMoWKtL9wE3bqZ-eUyaLMtgbUEUfHQb0jRhUtrJmMwg_ntnqCtXFy6Hy-UgdEtgRkCqBxN2MwoUZgBEnKEJUYwUkkN5jiYgpSoopeoSXeW8BwBFaTlBb0tju5gyXuQcbTCd2-Hv0NX4JTa5b9vkcg6xwdHj1XqD1413thuL0OCudvi9NU3INd4sqhWuYh1Td40uvDlkd_OXU_S5fPyoVsXz69O6WjwXlpa8KwSRQjBHdhwM8V54Adxaz-RWMbUtvaCCcKlKCsoJPjwXVjEjvDPGOBCOTdH9abdN8at3udPHkK07HEzjYp815YxKUfJyPqB3_9B97FMzvBsoASDnnIqBKk6UTTHn5LxuUzia9KMJ6NGwHgzr0bAeDbNfUK1ssQ</recordid><startdate>20201101</startdate><enddate>20201101</enddate><creator>Roca, Bernardino</creator><creator>Teira, R</creator><creator>Domingo, P</creator><creator>Geijo, P</creator><creator>Galindo, MJ</creator><creator>Lozano, F</creator><creator>Terron, A</creator><creator>Garrido, M</creator><creator>Suarez-Lozano, I</creator><creator>Vidal, F</creator><creator>Muñoz-Sanchez, P</creator><creator>Viciana, P</creator><creator>Ribera, E</creator><creator>Castaño, M</creator><creator>Martinez, E</creator><creator>Puig, T</creator><creator>Estrada, V</creator><creator>Deig, E</creator><creator>de la Fuente, B</creator><creator>Montero, M</creator><creator>Muñoz-Sanz, A</creator><creator>Sanchez, T</creator><creator>Romero-Palacios, A</creator><creator>Lacalle, JR</creator><general>Mary Ann Liebert, Inc</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7T2</scope><scope>7T5</scope><scope>7T7</scope><scope>7TK</scope><scope>7U7</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>M7N</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20201101</creationdate><title>Factors Associated with Nonsuppression of HIV Infection in the Spanish VACH Cohort</title><author>Roca, Bernardino ; Teira, R ; Domingo, P ; Geijo, P ; Galindo, MJ ; Lozano, F ; Terron, A ; Garrido, M ; Suarez-Lozano, I ; Vidal, F ; Muñoz-Sanchez, P ; Viciana, P ; Ribera, E ; Castaño, M ; Martinez, E ; Puig, T ; Estrada, V ; Deig, E ; de la Fuente, B ; Montero, M ; Muñoz-Sanz, A ; Sanchez, T ; Romero-Palacios, A ; Lacalle, JR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c254t-618663e1d40a1ff6f604ccf38b939b5f62614895209e642296c93a6feaaae06e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>AIDS/HIV</topic><topic>Antiretroviral agents</topic><topic>Body mass</topic><topic>Body mass index</topic><topic>Body size</topic><topic>CD4 antigen</topic><topic>Epidemics</topic><topic>Health risks</topic><topic>Health services</topic><topic>Hepatitis</topic><topic>Hepatitis C</topic><topic>HIV</topic><topic>Human immunodeficiency virus</topic><topic>Infections</topic><topic>Patients</topic><topic>Public health</topic><topic>Regression analysis</topic><topic>Ribonucleic acid</topic><topic>Risk analysis</topic><topic>Risk factors</topic><topic>RNA</topic><topic>Sexually transmitted diseases</topic><topic>STD</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Roca, Bernardino</creatorcontrib><creatorcontrib>Teira, R</creatorcontrib><creatorcontrib>Domingo, P</creatorcontrib><creatorcontrib>Geijo, P</creatorcontrib><creatorcontrib>Galindo, MJ</creatorcontrib><creatorcontrib>Lozano, F</creatorcontrib><creatorcontrib>Terron, A</creatorcontrib><creatorcontrib>Garrido, M</creatorcontrib><creatorcontrib>Suarez-Lozano, I</creatorcontrib><creatorcontrib>Vidal, F</creatorcontrib><creatorcontrib>Muñoz-Sanchez, P</creatorcontrib><creatorcontrib>Viciana, P</creatorcontrib><creatorcontrib>Ribera, E</creatorcontrib><creatorcontrib>Castaño, M</creatorcontrib><creatorcontrib>Martinez, E</creatorcontrib><creatorcontrib>Puig, T</creatorcontrib><creatorcontrib>Estrada, V</creatorcontrib><creatorcontrib>Deig, E</creatorcontrib><creatorcontrib>de la Fuente, B</creatorcontrib><creatorcontrib>Montero, M</creatorcontrib><creatorcontrib>Muñoz-Sanz, A</creatorcontrib><creatorcontrib>Sanchez, T</creatorcontrib><creatorcontrib>Romero-Palacios, A</creatorcontrib><creatorcontrib>Lacalle, JR</creatorcontrib><creatorcontrib>on Behalf of the Spanish VACH Cohort Group</creatorcontrib><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>AIDS research and human retroviruses</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Roca, Bernardino</au><au>Teira, R</au><au>Domingo, P</au><au>Geijo, P</au><au>Galindo, MJ</au><au>Lozano, F</au><au>Terron, A</au><au>Garrido, M</au><au>Suarez-Lozano, I</au><au>Vidal, F</au><au>Muñoz-Sanchez, P</au><au>Viciana, P</au><au>Ribera, E</au><au>Castaño, M</au><au>Martinez, E</au><au>Puig, T</au><au>Estrada, V</au><au>Deig, E</au><au>de la Fuente, B</au><au>Montero, M</au><au>Muñoz-Sanz, A</au><au>Sanchez, T</au><au>Romero-Palacios, A</au><au>Lacalle, JR</au><aucorp>on Behalf of the Spanish VACH Cohort Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Factors Associated with Nonsuppression of HIV Infection in the Spanish VACH Cohort</atitle><jtitle>AIDS research and human retroviruses</jtitle><date>2020-11-01</date><risdate>2020</risdate><volume>36</volume><issue>11</issue><spage>927</spage><epage>932</epage><pages>927-932</pages><issn>0889-2229</issn><eissn>1931-8405</eissn><abstract>We aim to determine the prevalence of HIV nonsuppression and factors associated with it. This is a cross-sectional multicenter study carried out in January 2016 with data of the VACH Cohort, a registry participated by 23 hospitals from most regions of Spain. The prevalence of HIV nonsuppression, defined as HIV RNA ≥200 copies/mL, is documented. The possible association of HIV nonsuppression with sociodemographic and clinical variables is assessed with a logistic regression analysis. A total of 30,843 adult patients are included; 7,358 of them (23.86%) have nonsuppressed HIV. An association is found between nonsuppression of HIV and the following variables: lower body mass index, lower age of patients in their last registered visit, lower number of visits carried out during follow-up, lower last available CD4 cell count, higher age of patients at the time of their HIV infection diagnosis, higher lowest available CD4 cell count, higher highest available HIV RNA, enrolment in the Cohort in first years of the HIV epidemic, region of Spain where the patient is attended other than Andalusia, HIV risk factor other than sexual, occurrence of death during follow-up, hepatitis C coinfection, being a smoker, pertaining to groups A1 or A2 of the CDC groups classification, and not taking antiretroviral treatment, p < .001 in all cases. HIV nonsuppression is still common with the effective antiretroviral treatment nowadays available. HIV nonsuppression is associated with HIV risk factor other than sexual, hepatitis C coinfection, and being a smoker, among other factors.</abstract><cop>New Rochelle</cop><pub>Mary Ann Liebert, Inc</pub><doi>10.1089/aid.2020.0016</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0889-2229 |
| ispartof | AIDS research and human retroviruses, 2020-11, Vol.36 (11), p.927-932 |
| issn | 0889-2229 1931-8405 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2432865457 |
| source | Alma/SFX Local Collection |
| subjects | AIDS/HIV Antiretroviral agents Body mass Body mass index Body size CD4 antigen Epidemics Health risks Health services Hepatitis Hepatitis C HIV Human immunodeficiency virus Infections Patients Public health Regression analysis Ribonucleic acid Risk analysis Risk factors RNA Sexually transmitted diseases STD |
| title | Factors Associated with Nonsuppression of HIV Infection in the Spanish VACH Cohort |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T11%3A33%3A45IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Factors%20Associated%20with%20Nonsuppression%20of%20HIV%20Infection%20in%20the%20Spanish%20VACH%20Cohort&rft.jtitle=AIDS%20research%20and%20human%20retroviruses&rft.au=Roca,%20Bernardino&rft.aucorp=on%20Behalf%20of%20the%20Spanish%20VACH%20Cohort%20Group&rft.date=2020-11-01&rft.volume=36&rft.issue=11&rft.spage=927&rft.epage=932&rft.pages=927-932&rft.issn=0889-2229&rft.eissn=1931-8405&rft_id=info:doi/10.1089/aid.2020.0016&rft_dat=%3Cproquest_cross%3E2460087426%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2460087426&rft_id=info:pmid/&rfr_iscdi=true |