Frequency and spectrum of founder and non-founder BRCA1 and BRCA2 mutations in a large series of Russian breast cancer and ovarian cancer patients

Background The spectrum of BRCA1 and BRCA2 mutations in Slavic countries is characterized by a high prevalence of founder alleles. Methods We analyzed a large data set of Russian breast cancer (BC) and ovarian cancer (OC) patients, who were subjected to founder mutation tests or full-length BRCA1 an...

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Veröffentlicht in:	Breast cancer research and treatment 2020-11, Vol.184 (1), p.229-235
Hauptverfasser:	Sokolenko, Anna P., Sokolova, Tatiana N., Ni, Valeria I., Preobrazhenskaya, Elena V., Iyevleva, Aglaya G., Aleksakhina, Svetlana N., Romanko, Alexandr A., Bessonov, Alexandr A., Gorodnova, Tatiana V., Anisimova, Elena I., Savonevich, Elena L., Bizin, Ilya V., Stepanov, Ilya A., Krivorotko, Petr V., Berlev, Igor V., Belyaev, Alexey M., Togo, Alexandr V., Imyanitov, Evgeny N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis BRCA mutations Breast cancer Cancer Cancer patients Care and treatment Epidemiology Genetic aspects Medicine Medicine & Public Health Oncology Ovarian cancer
Online-Zugang:	Volltext
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