IL6R is a target of miR‐197 in human keratinocytes

Psoriasis is a chronic inflammatory disorder with cutaneous and systemic manifestations and substantial negative effects on patients’ quality of life. MicroRNAs (miRNAs) are post‐transcriptional regulators of gene expression that play a role in the pathogenesis of psoriasis. Previously studies, from...

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Veröffentlicht in:	Experimental dermatology 2021-08, Vol.30 (8), p.1177-1186
Hauptverfasser:	Masalha, Moamen, Gur‐Wahnon, Devorah, Meningher, Tal, Ben‐Dov, Iddo Z., Kassem, Riad, Sidi, Yechezkel, Avni, Dror
Format:	Artikel
Sprache:	eng
Schlagworte:	Argonaute 2 protein Cathepsins - metabolism Cell Proliferation Cysteine Endopeptidases - metabolism Down-Regulation Gene expression Gene Expression Regulation HaCaT Cells Humans IL6R Immune system Immunoprecipitation Inflammatory diseases Interleukin 6 Interleukin 6 receptors Keratinocytes Keratinocytes - metabolism MicroRNAs MicroRNAs - metabolism miRNA miR‐197 PAR‐CLIP Psoriasis Psoriasis - metabolism Quality of Life Receptors, Interleukin-6 - metabolism Therapeutic targets Transcription Transcriptional Activation Transcriptomes
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