Activity of cefepime/zidebactam against MDR Escherichia coli isolates harbouring a novel mechanism of resistance based on four-amino-acid inserts in PBP3

Abstract Background Recent reports reveal the emergence of Escherichia coli isolates harbouring a novel resistance mechanism based on four-amino-acid inserts in PBP3. These organisms concomitantly expressed ESBLs or/and serine-/metallo-carbapenemases and were phenotypically detected by elevated aztr...

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Veröffentlicht in:Journal of antimicrobial chemotherapy 2020-12, Vol.75 (12), p.3563-3567
Hauptverfasser: Bhagwat, Sachin S, Hariharan, Periasamy, Joshi, Prashant R, Palwe, Snehal R, Shrivastava, Rahul, Patel, Mahesh V, Devanga Ragupathi, Naveen Kumar, Bakthavatchalam, Yamuna Devi, Ramesh, Mayur S, Soman, Rajeev, Veeraraghavan, Balaji
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Sprache:eng
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