Brain changes associated with negative symptoms in clinical high risk for psychosis: A systematic review

•Negative symptoms of schizophrenia often occur early in those at clinical high risk.•The biological basis of negative symptoms are poorly understood in those at risk.•Some evidence for inverse relationship between negative symptoms and grey matter.•Negative symptoms are associated with changes in r...

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Veröffentlicht in:Neuroscience and biobehavioral reviews 2020-11, Vol.118, p.367-383
Hauptverfasser: Metzak, Paul D., Devoe, Daniel J., Iwaschuk, Amanda, Braun, Amy, Addington, Jean
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Sprache:eng
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