Spatiotemporal regulation of GABA concentration in extracellular space by gliotransmission crucial for extrasynaptic receptor-mediated improvement of sensory tuning performance in schizophrenia

In schizophrenic patients, sensory tuning performance tends to be deteriorated (i.e., flattened sensory tuning), for which impaired intracortical tonic inhibition arising from a reduction in GABA concentration in extracellular space might be responsible. The δ subunit-containing GAB A A receptor, lo...

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Veröffentlicht in:	Journal of computational neuroscience 2020-08, Vol.48 (3), p.317-332
Hauptverfasser:	Hoshino, Osamu, Kameno, Rikiya, Kubo, Jin, Watanabe, Kazuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine Human Genetics Neurology Neurosciences Theory of Computation
Online-Zugang:	Volltext
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